The average train between Strasbourg and Main takes 3h 37m and the fastest train takes 2h 54m. The train service runs several times per day from Strasbourg to Main. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 5 times a day between Strasbourg and Main. The earliest departure is at 9:08 AM in the morning, and the last departure from Strasbourg is at 8:59 PM which arrives into Main at 1:17 AM. All services require a transfer, and take on average 3h 37m. The schedules shown below are for the next available departures.

3h 24m • 1 change

3h 23m • 1 change

3h 37m • 1 change

3h 19m • 1 change

3h 24m • 1 change

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3h 37m • 1 change

3h 19m • 1 change

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3h 23m • 1 change

3h 37m • 1 change

3h 19m • 1 change

3h 24m • 1 change

3h 23m • 1 change

3h 37m • 1 change

3h 19m • 1 change

3h 24m • 1 change

3h 34m • 1 change

3h 23m • 1 change

3h 37m • 1 change

3h 34m • 1 change

3h 23m • 1 change

3h 37m • 1 change

3h 33m • 1 change
Want to know about travelling from Strasbourg to Main? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Strasbourg to Main. However, there are services departing from Strasbourg station and arriving at Main station via Mannheim, Hauptbahnhof. The journey, including transfers, takes approximately 3h 37m.
Strasbourg to Main train services, operated by Deutsche Bahn Intercity (DB IC), depart from Strasbourg Bahnhof station.
Strasbourg to Main train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Mainz, Römisches Theater station.
Book your Strasbourg to Main train tickets online with Deutsche Bahn Intercity (DB IC), Deutsche Bahn Regio (DB Regional) and TGV inOui.
The distance between Strasbourg and Main is 161.8 km. The road distance is 210 km.
You can take a train from Strasbourg Bahnhof to Mainz, Römisches Theater via Mannheim, Hauptbahnhof in around 2h 42m.