The average train between St. Louis and Chicago takes 5h 7m and the fastest train takes 4h 55m. The train service runs several times per day from St. Louis to Chicago. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 5 times a day between St. Louis and Chicago. The earliest departure is at 4:30 AM at night, and the last departure from St. Louis is at 5:40 PM which arrives into Chicago at 10:43 PM. All services run direct with no transfers required, and take on average 5h 7m. The schedules shown below are for the next available departures.
Want to know about travelling from St. Louis to Chicago? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
Yes, there is a direct train departing from St. Louis station and arriving at Chicago station. Services depart 5 times a day, and operate Once daily. The journey takes approximately 5h 7m.
St. Louis to Chicago train services, operated by Amtrak, depart from St. Louis station.
St. Louis to Chicago train services, operated by Amtrak, arrive at Chicago Union Station.
Book your St. Louis to Chicago train tickets online with Amtrak.
The distance between St. Louis and Chicago is 421.9 km. The road distance is 452 km.
Amtrak operates a train from St. Louis to Chicago Union Station 5 times a day. Tickets cost $75–170 and the journey takes 4h 55m.
