The train between St. Louis and Brookline takes 28h 29m. There is at least one train per day from St. Louis to Brookline. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run once daily between St. Louis and Brookline. The earliest departure is at 2:55 PM in the afternoon, and the last departure from St. Louis is at 2:55 PM which arrives into Brookline at 8:24 PM. All services require a transfer, and take on average 28h 29m. The schedules shown below are for the next available departures.
Want to know about travelling from St. Louis to Brookline? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from St. Louis to Brookline. However, there are services departing from St. Louis station and arriving at Brookline station via Chicago Union Station station. The journey, including transfers, takes approximately 28h 29m.
St. Louis to Brookline train services, operated by Amtrak, depart from St. Louis station.
St. Louis to Brookline train services, operated by Amtrak, arrive at Boston station.
Book your St. Louis to Brookline train tickets online with Amtrak.
The distance between St. Louis and Brookline is 1,661.3 km. The road distance is 2,082 km.
You can take a train from St. Louis to Boston via Chicago Union Station in around 27h 49m.
