The average train between Philadelphia and Brookline takes 5h 43m and the fastest train takes 4h 56m. There is a train service every few hours from Philadelphia to Brookline. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Philadelphia and Brookline. The earliest departure is at 12:33 AM at night, and the last departure from Philadelphia is at 8:04 PM which arrives into Brookline at 1:04 AM. All services require a transfer, and take on average 5h 43m. The schedules shown below are for the next available departures.

5h 11m • 1 change

5h 22m • 1 change
Arrives next day

6h 11m • 1 change

8h 51m • 1 change

4h 56m • 1 change

5h 7m • 1 change

5h 3m • 1 change

8h 51m • 1 change

4h 56m • 1 change

5h 7m • 1 change

5h 3m • 1 change

8h 51m • 1 change

4h 56m • 1 change

5h 7m • 1 change

5h 3m • 1 change

9h 25m • 1 change

5h 56m • 1 change

6h 11m • 1 change

5h 56m • 1 change
Want to know about travelling from Philadelphia to Brookline? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Philadelphia to Brookline. However, there are services departing from Philadelphia station and arriving at Brookline station via Ny Moynihan Train Hall At Penn Station station. The journey, including transfers, takes approximately 5h 43m.
Philadelphia to Brookline train services, operated by Amtrak Acela, depart from 30th Street Station.
Philadelphia to Brookline train services, operated by Amtrak Acela, arrive at Boston station.
Book your Philadelphia to Brookline train tickets online with Amtrak Acela, Amtrak Northeast Regional and Amtrak.
The distance between Philadelphia and Brookline is 429.6 km. The road distance is 515 km.
You can take a train from 30th Street Station to Boston via Ny Moynihan Train Hall At Penn Station in around 5h 49m.