The average train between Slough and Middlesbrough takes 4h 21m and the fastest train takes 3h 42m. There is a train service every few hours from Slough to Middlesbrough. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Slough and Middlesbrough. The earliest departure is at 5:38 AM in the morning, and the last departure from Slough is at 10:02 PM which arrives into Middlesbrough at 6:35 AM. All services require a transfer at London Paddington and take an average of 4h 21m. The schedules shown below are for the next available departures.



4h 1m • 3 changes



3h 42m • 3 changes



3h 59m • 3 changes



3h 59m • 3 changes



4h 1m • 3 changes



3h 42m • 3 changes



3h 59m • 3 changes



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4h 1m • 3 changes



3h 42m • 3 changes



3h 59m • 3 changes



3h 59m • 3 changes
Want to know about travelling from Slough to Middlesbrough? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Slough to Middlesbrough. However, there are services departing from Slough station and arriving at Middlesbrough station via York. The journey, including transfers, takes approximately 4h 21m.
Slough to Middlesbrough train services, operated by Elizabeth Line (TfL), depart from King's Cross station.
Slough to Middlesbrough train services, operated by Elizabeth Line (TfL), arrive at Middlesbrough station.
Book your Slough to Middlesbrough train tickets online with Elizabeth Line (TfL), London Underground (Tube) and 3 other operators.
The distance between Slough and Middlesbrough is 343.7 km. The road distance is 417 km.
You can take a train from Slough to Middlesbrough via London Paddington, Paddington, King's Cross St. Pancras station, King's Cross, and York in around 4h 5m.