The average train between Slough and Brussels takes 3h 2m and the fastest train takes 2h 39m. The train service runs several times per day from Slough to Brussels. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Slough and Brussels. The earliest departure is at 6:03 AM in the morning, and the last departure from Slough is at 6:55 PM which arrives into Brussels at 10:35 PM. All services require a transfer at London Paddington and take an average of 3h 2m. The schedules shown below are for the next available departures.


4h 12m • 2 changes


3h 57m • 2 changes


4h 3m • 2 changes


4h 3m • 2 changes


4h 2m • 2 changes


4h 12m • 2 changes


3h 57m • 2 changes


4h 3m • 2 changes


4h 2m • 2 changes


4h 12m • 2 changes


3h 57m • 2 changes


4h 3m • 2 changes


4h 2m • 2 changes


4h 12m • 2 changes


3h 57m • 2 changes


4h 3m • 2 changes


4h 2m • 2 changes


4h 12m • 2 changes


3h 57m • 2 changes


4h 3m • 2 changes


4h 1m • 2 changes


4h 2m • 2 changes


4h 2m • 2 changes


4h 2m • 2 changes
Want to know about travelling from Slough to Brussels? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Slough to Brussels. However, there are services departing from Slough station and arriving at Brussels station via Brussel-Zuid / Bruxelles-Midi. The journey, including transfers, takes approximately 3h 2m.
Slough to Brussels train services, operated by Great Western Railway (GWR), depart from London St Pancras Intl station.
Slough to Brussels train services, operated by Great Western Railway (GWR), arrive at Brussel-Zuid / Bruxelles-Midi station.
Book your Slough to Brussels train tickets online with Great Western Railway (GWR), London Underground (Tube) and 2 other operators.
The distance between Slough and Brussels is 352.3 km. The road distance is 405 km.
Eurostar operates a train from London St Pancras Intl to Brussel-Zuid / Bruxelles-Midi every 4 hours. Tickets cost €120–210 and the journey takes 2h 1m.