The average train between Slough and Brussels takes 3h 36m and the fastest train takes 3h 15m. The train service runs several times per day from Slough to Brussels. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Slough and Brussels. The earliest departure is at 6:08 AM in the morning, and the last departure from Slough is at 7:08 PM which arrives into Brussels at 11:34 PM. All services require a transfer at Farringdon Without and take an average of 3h 36m. The schedules shown below are for the next available departures.


4h 26m • 2 changes


4h 15m • 2 changes


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4h 15m • 2 changes


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4h 22m • 2 changes


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4h 22m • 2 changes
Want to know about travelling from Slough to Brussels? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Slough to Brussels. However, there are services departing from Slough station and arriving at Brussels station via Farringdon Without. The journey, including transfers, takes approximately 3h 36m.
Slough to Brussels train services, operated by Elizabeth Line (TfL), depart from Slough station.
Slough to Brussels train services, operated by Elizabeth Line (TfL), arrive at Brussel-Zuid / Bruxelles-Midi station.
Book your Slough to Brussels train tickets online with Elizabeth Line (TfL), Thameslink and Eurostar.
The distance between Slough and Brussels is 352.3 km. The road distance is 408 km.
You can take a train from Slough to Brussel-Zuid / Bruxelles-Midi via Farringdon Without, Farringdon, and London St Pancras Intl in around 3h 46m.