The average train between Slough and Melksham takes 2h 4m and the fastest train takes 1h 20m. The train service runs several times per day from Slough to Melksham. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 3 hours between Slough and Melksham. The earliest departure is at 7:24 AM in the morning, and the last departure from Slough is at 11:51 PM which arrives into Melksham at 6:28 AM. All services require a transfer at Reading and take an average of 2h 4m. The schedules shown below are for the next available departures.


1h 37m • 2 changes


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1h 47m • 2 changes


1h 21m • 2 changes


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1h 33m • 2 changes


1h 37m • 2 changes


1h 29m • 2 changes


1h 58m • 2 changes


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1h 45m • 2 changes
Want to know about travelling from Slough to Melksham? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Slough to Melksham. However, there are services departing from Slough station and arriving at Melksham station via Reading. The journey, including transfers, takes approximately 2h 4m.
Slough to Melksham train services, operated by Elizabeth Line (TfL), depart from Slough station.
Slough to Melksham train services, operated by Elizabeth Line (TfL), arrive at Melksham station.
Book your Slough to Melksham train tickets online with Elizabeth Line (TfL) and Great Western Railway (GWR).
The distance between Slough and Melksham is 108.1 km. The road distance is 131 km.
You can take a train from Slough to Melksham via Reading and Swindon in around 2h 27m.