The average bus between Slough and Ayr takes 16h 8m and the fastest bus takes 12h 55m. The bus service runs several times per day from Slough to Ayr. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Slough and Ayr. The earliest departure is at 12:00 AM at night, and the last departure from Slough is at 7:23 PM which arrives into Ayr at 8:52 AM. All services require a transfer at Heathrow Terminal 5 and take an average of 16h 8m. The schedules shown below are for the next available departures.



19h 55m • 3 changes



14h 20m • 3 changes
Arrives next day



13h 25m • 3 changes



19h 55m • 3 changes



14h 50m • 3 changes
Arrives next day



13h 29m • 3 changes



20h 25m • 3 changes



14h 7m • 3 changes
Arrives next day



15h 5m • 3 changes



20h 25m • 3 changes



14h 16m • 3 changes
Arrives next day



12h 55m • 3 changes
Want to know about travelling from Slough to Ayr? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Slough to Ayr. However, there are services departing from Slough station and arriving at Ayr station via Birmingham Coach Station station. The journey, including transfers, takes approximately 16h 8m.
Slough to Ayr bus services, operated by Thames Valley Buses, depart from Heathrow Terminal 5 station.
Slough to Ayr bus services, operated by Thames Valley Buses, arrive at Ayr Bus Station.
Book your Slough to Ayr bus tickets online with Thames Valley Buses, National Express and 2 other operators.
The distance between Slough and Ayr is 514.2 km. The road distance is 738 km.
You can take a bus from Wellington Street Stop A to Ayr Bus Station via Heathrow Terminal 5, Birmingham Coach Station, and Buchanan Bus Station in around 13h 34m.