The average train between Sheffield and Holyhead takes 4h 26m and the fastest train takes 3h 55m. There is a train service every few hours from Sheffield to Holyhead. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Sheffield and Holyhead. The earliest departure is at 5:08 AM in the morning, and the last departure from Sheffield is at 10:11 PM which arrives into Holyhead at 8:51 AM. All services require a transfer, and take on average 4h 26m. The schedules shown below are for the next available departures.

4h 34m • 1 change

4h 27m • 1 change

4h 11m • 1 change

3h 56m • 1 change

4h 34m • 1 change

4h 27m • 1 change

4h 11m • 1 change

3h 56m • 1 change

4h 34m • 1 change

4h 27m • 1 change

4h 11m • 1 change

3h 56m • 1 change
Want to know about travelling from Sheffield to Holyhead? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Sheffield to Holyhead. However, there are services departing from Sheffield station and arriving at Holyhead station via Manchester Oxford Road. The journey, including transfers, takes approximately 4h 26m.
Sheffield to Holyhead train services, operated by TransPennine Express, depart from Sheffield station.
Sheffield to Holyhead train services, operated by TransPennine Express, arrive at Holyhead station.
Book your Sheffield to Holyhead train tickets online with TransPennine Express, Transport for Wales and East Midlands Railways.
The distance between Sheffield and Holyhead is 210.4 km. The road distance is 268 km.
You can take a train from Sheffield to Holyhead via Manchester Oxford Road in around 4h 44m.