The average train between Santander and Avignon takes 22h 18m and the fastest train takes 14h 50m. The train service runs several times per day from Santander to Avignon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 3 times a day between Santander and Avignon. The earliest departure is at 6:40 AM in the morning, and the last departure from Santander is at 7:20 PM which arrives into Avignon at 8:25 PM. All services require a transfer at Madrid Chamartín and take an average of 22h 18m. The schedules shown below are for the next available departures.
Arrives next day




25h 47m • 4 changes
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24h 25m • 4 changes
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25h 5m • 4 changes




14h 50m • 4 changes
Arrives next day




24h 25m • 4 changes
Arrives next day




25h 25m • 4 changes




14h 50m • 4 changes
Arrives next day




24h 25m • 4 changes
Arrives next day




25h 25m • 4 changes




14h 50m • 4 changes
Arrives next day




24h 25m • 4 changes
Arrives next day




25h 25m • 4 changes
Want to know about travelling from Santander to Avignon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Santander to Avignon. However, there are services departing from Santander station and arriving at Avignon station via Madrid Chamartín. The journey, including transfers, takes approximately 22h 18m.
Santander to Avignon train services, operated by Renfe Viajeros, depart from Santander station.
Santander to Avignon train services, operated by Renfe Viajeros, arrive at Avignon Centre station.
Book your Santander to Avignon train tickets online with Renfe Viajeros, Renfe Cercanias and 3 other operators.
The distance between Santander and Avignon is 694.1 km. The road distance is 1,516 km.
You can take a train from Santander to Avignon Centre via Madrid Chamartín, Madrid-Atocha Cercanías, Madrid-Puerta de Atocha-Almudena Grandes, Barcelona-Sants, and Narbonne in around 14h.