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Santa Ana to Buffalo trains

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Trip Overview

The train between Santa Ana and Buffalo takes 2d 19h. The train runs, on average, 4 times per week from Santa Ana to Buffalo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

2d 19h
Duration
2,747 mi
Distance
$838
Average price
4 times a week
Frequency

Santa Ana to Buffalo train times

Trains run 4 times a week between Santa Ana and Buffalo. The earliest departure is at 4:04 PM in the afternoon, and the last departure from Santa Ana is at 5:26 PM which arrives into Buffalo at 3:40 PM. All services require a transfer at Fullerton Amtrak Station and take an average of 2d 19h. The schedules shown below are for the next available departures.

Departing Friday, October 9, 2026

  •  → 

    Arrives +3 days

    Metrolink TrainsAmtrakAmtrakAmtrak2d 19h • 3 changes

Departing Saturday, October 10, 2026

  •  → 

    Arrives +3 days

    AmtrakAmtrakAmtrakAmtrak2d 20h • 3 changes

Departing Sunday, October 11, 2026

  •  → 

    Arrives +3 days

    AmtrakAmtrakAmtrakAmtrak2d 20h • 3 changes

Departing Monday, October 12, 2026

  •  → 

    Arrives +3 days

    Metrolink TrainsAmtrakAmtrakAmtrak2d 19h • 3 changes

Frequently asked questions

Want to know about travelling from Santa Ana to Buffalo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Santa Ana to Buffalo.ExpandLaunch map view
  • Distance: 2,746.6 mi
  • Duration: 2d 19h

What companies run services between Santa Ana, CA, USA and Buffalo, NY, USA?

You can take a train from Santa Ana to Buffalo via Fullerton Amtrak Station, Chicago Union Station, and Buffalo Depew Station in around 2d 8h.

Operators