The average train between Reading and Holyhead takes 6h 27m and the fastest train takes 5h 33m. The train service runs several times per day from Reading to Holyhead. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Reading and Holyhead. The earliest departure is at 6:15 AM in the morning, and the last departure from Reading is at 8:42 PM which arrives into Holyhead at 8:24 AM. All services require a transfer, and take on average 6h 27m. The schedules shown below are for the next available departures.

5h 37m • 1 change

5h 34m • 1 change

5h 40m • 1 change

5h 48m • 1 change

5h 33m • 1 change

5h 37m • 1 change

5h 34m • 1 change

5h 40m • 1 change

5h 33m • 1 change

5h 37m • 1 change

5h 34m • 1 change

5h 40m • 1 change

5h 33m • 1 change

5h 37m • 1 change

5h 34m • 1 change

5h 40m • 1 change

5h 37m • 1 change

5h 34m • 1 change

5h 36m • 1 change

5h 33m • 1 change

5h 40m • 1 change

5h 34m • 1 change

5h 33m • 1 change
Arrives next day

12h 9m • 1 change

5h 33m • 1 change

5h 37m • 1 change

5h 34m • 1 change

5h 40m • 1 change
Want to know about travelling from Reading to Holyhead? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Reading to Holyhead. However, there are services departing from Reading station and arriving at Holyhead station via Stafford. The journey, including transfers, takes approximately 6h 27m.
Reading to Holyhead train services, operated by Cross Country, depart from Reading station.
Reading to Holyhead train services, operated by Cross Country, arrive at Holyhead station.
Book your Reading to Holyhead train tickets online with Cross Country and Avanti West Coast.
The distance between Reading and Holyhead is 322.9 km. The road distance is 411 km.
You can take a train from Reading to Holyhead via Stafford in around 5h 43m.