The average train between Southampton and Holyhead takes 7h 24m and the fastest train takes 6h 33m. The train service runs several times per day from Southampton to Holyhead. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Southampton and Holyhead. The earliest departure is at 5:15 AM in the morning, and the last departure from Southampton is at 7:15 PM which arrives into Holyhead at 8:25 AM. All services require a transfer, and take on average 7h 24m. The schedules shown below are for the next available departures.

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Want to know about travelling from Southampton to Holyhead? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Southampton to Holyhead. However, there are services departing from Southampton station and arriving at Holyhead station via Stafford. The journey, including transfers, takes approximately 7h 24m.
Southampton to Holyhead train services, operated by Cross Country, depart from Southampton Central station.
Southampton to Holyhead train services, operated by Cross Country, arrive at Holyhead station.
Book your Southampton to Holyhead train tickets online with Cross Country and Avanti West Coast.
The distance between Southampton and Holyhead is 346.7 km. The road distance is 486 km.
You can take a train from Southampton Central to Holyhead via Stafford in around 6h 44m.