The average train between Prestwick and Manchester takes 4h 42m and the fastest train takes 3h 59m. There is a train service every few hours from Prestwick to Manchester. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Prestwick and Manchester. The earliest departure is at 5:20 AM in the morning, and the last departure from Prestwick is at 11:10 PM which arrives into Manchester at 7:53 AM. All services require a transfer at Glasgow Central and take an average of 4h 42m. The schedules shown below are for the next available departures.


4h 30m • 2 changes


4h 43m • 2 changes


4h 30m • 2 changes


4h 10m • 2 changes


4h 33m • 2 changes


4h 13m • 2 changes


4h • 2 changes


4h 11m • 2 changes


4h 33m • 2 changes


4h 13m • 2 changes


4h • 2 changes


4h 11m • 2 changes
Want to know about travelling from Prestwick to Manchester? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Prestwick to Manchester. However, there are services departing from Prestwick station and arriving at Manchester station via Glasgow Central. The journey, including transfers, takes approximately 4h 42m.
Prestwick to Manchester train services, operated by ScotRail, depart from Prestwick Town station.
Prestwick to Manchester train services, operated by ScotRail, arrive at Manchester Oxford Road station.
Book your Prestwick to Manchester train tickets online with ScotRail, Avanti West Coast and 3 other operators.
The distance between Prestwick and Manchester is 271.7 km. The road distance is 416 km.
You can take a train from Prestwick Town to Manchester Oxford Road via Glasgow Central and Preston in around 4h 22m.