The average train between Prague and Meissen takes 3h 3m and the fastest train takes 2h 56m. The train service runs several times per day from Prague to Meissen. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Prague and Meissen. The earliest departure is at 6:41 AM in the morning, and the last departure from Prague is at 6:41 PM which arrives into Meissen at 10:07 PM. All services require a transfer, and take on average 3h 3m. The schedules shown below are for the next available departures.

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3h 26m • 1 change

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2h 56m • 1 change

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Want to know about travelling from Prague to Meissen? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Prague to Meissen. However, there are services departing from Prague station and arriving at Meissen station via Dresden-Neustadt. The journey, including transfers, takes approximately 3h 3m.
Prague to Meissen train services, operated by České dráhy (ČD), depart from Praha-Holesovice station.
Prague to Meissen train services, operated by České dráhy (ČD), arrive at Dresden-Neustadt station.
The distance between Prague and Meissen is 136.8 km. The road distance is 212 km.
České dráhy (ČD) operates a train from Praha-Holesovice to Dresden-Neustadt every 4 hours. Tickets cost €22–35 and the journey takes 2h 17m. Three other operators also service this route.