The average train between Prague and Mannheim takes 10h 2m and the fastest train takes 8h 48m. The train service runs several times per day from Prague to Mannheim. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Prague and Mannheim. The earliest departure is at 6:41 AM in the morning, and the last departure from Prague is at 6:41 PM which arrives into Mannheim at 11:29 AM. All services require a transfer at Dresden Bahnhof Neustadt and take an average of 10h 2m. The schedules shown below are for the next available departures.


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Want to know about travelling from Prague to Mannheim? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Prague to Mannheim. However, there are services departing from Prague station and arriving at Mannheim station via Dresden-Neustadt. The journey, including transfers, takes approximately 10h 2m.
Prague to Mannheim train services, operated by Danish Railways (DSB), depart from Praha-Holesovice station.
Prague to Mannheim train services, operated by Danish Railways (DSB), arrive at Mannheim, Hauptbahnhof station.
Book your Prague to Mannheim train tickets online with Danish Railways (DSB), Deutsche Bahn Intercity (DB IC) and 3 other operators.
The distance between Prague and Mannheim is 432.5 km. The road distance is 752 km.
You can take a train from Praha-Holesovice to Mannheim, Hauptbahnhof via Dresden Bahnhof Neustadt and Frankfurt in around 8h 22m.