The average train between Prague and Mannheim takes 10h 6m and the fastest train takes 8h 22m. The train service runs several times per day from Prague to Mannheim. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Prague and Mannheim. The earliest departure is at 5:35 AM in the morning, and the last departure from Prague is at 5:35 PM which arrives into Mannheim at 9:21 AM. All services require a transfer at Schwandorf and take an average of 10h 6m. The schedules shown below are for the next available departures.



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Want to know about travelling from Prague to Mannheim? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Prague to Mannheim. However, there are services departing from Prague station and arriving at Mannheim station via Schwandorf. The journey, including transfers, takes approximately 10h 6m.
Prague to Mannheim train services, operated by ÖBB EuroCity, depart from Praha Hlavni Nadrazi station.
Prague to Mannheim train services, operated by ÖBB EuroCity, arrive at Mannheim, Hauptbahnhof station.
Book your Prague to Mannheim train tickets online with ÖBB EuroCity, Deutsche Bahn Regio (DB Regional) and Deutsche Bahn Intercity (DB IC).
The distance between Prague and Mannheim is 432.5 km. The road distance is 642 km.
You can take a train from Praha Hlavni Nadrazi to Mannheim, Hauptbahnhof via Schwandorf, Nürnberg Hbf, and Frankfurt in around 9h 10m.