There are 8 ways to get from Prague to Mannheim by train, bus, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Train via Nürnberg ZOB  •  6 h 55 min

  1. Ice / ...
  2. Ice / ...

$103 - $158

Cheapest option

Bus  •  7 h 10 min

  1. N109 / ...

$18 - $55

6 alternative options

Train  •  7 h 15 min

$95 - $140

Bus Eurolines DE  •  9 h 45 min

  1. 851 / ...

$60 - $87

Drive  •  4 h 35 min

  1. 320.8 miles

$65 - $100

Fly Prague to Frankfurt, train  •  4 h 24 min

  1. PRG - FRA

$79 - $257

Bus to Dresden, fly to Frankfurt, train  •  5 h 16 min

  1. DRS - FRA

$93 - $292

Fly Prague to Cologne/Bonn Apt, train  •  6 h 1 min

  1. PRG - CGN

$99 - $280

What companies run services between Prague, Czech Republic and Mannheim, Germany?

You can take a train from Prague to Mannheim via Nürnberg ZOB, Nürnberg Hbf, and Frankfurt(Main)Hbf in around 6 h 55 min. Alternatively, FlixBus operates a bus from Prague to Mannheim twice daily. Tickets cost $30 - $55 and the journey takes 7 h 10 min. RegioJet also services this route once daily.

Airlines
Lufthansa
Website
lufthansa.com
Flights from Prague to Frankfurt
Ave. Duration
1 h 8 min
When
Every day
Estimated price
$100 - $480
Flights from Prague to Frankfurt via Munich
Ave. Duration
3 h
When
Every day
Estimated price
$100 - $480
Flights from Dresden to Frankfurt
Ave. Duration
1 h 5 min
When
Every day
Estimated price
$85 - $290
Flights from Dresden to Frankfurt via Munich
Ave. Duration
2 h 56 min
When
Every day
Estimated price
$85 - $290
Flights from Dresden to Frankfurt via Dusseldorf
Ave. Duration
2 h 55 min
When
Every day
Estimated price
$45 - $210
Flights from Prague to Cologne/Bonn Apt via Munich
Ave. Duration
3 h 6 min
When
Every day
Estimated price
$160 - $850
CSA
Website
csa.cz
Flights from Prague to Frankfurt
Ave. Duration
1 h 30 min
When
Every day
Estimated price
$60 - $360
Eurowings
Website
eurowings.com
Flights from Prague to Cologne/Bonn Apt
Ave. Duration
1 h 15 min
When
Every day
Estimated price
$40 - $300
Flights from Prague to Cologne/Bonn Apt via Hamburg
Ave. Duration
3 h 30 min
When
Sunday
Estimated price
$40 - $300
Austrian Airlines
Website
austrian.com
Flights from Prague to Cologne/Bonn Apt via Vienna
Ave. Duration
3 h 30 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$40 - $300
Train operators
Czech Railways (ČD)
Phone
+420 221 111 122
Email
info@cd.cz
Website
cd.cz
Train from Praha hl.n. (Autobusová St. Wilsonova) to Nürnberg ZOB
Ave. Duration
3 h 35 min
Frequency
Every 2 hours
Estimated price
$40 - $65
Website
cd.cz
Train from Praha hl.n. (Autobusová St. Wilsonova) to Mannheim Hbf (Busbahnhof)
Ave. Duration
7 h 15 min
Frequency
3 times a day
Estimated price
$95 - $140
Website
cd.cz
Deutsche Bahn
Phone
+49 0180 6 99 66 33
Website
bahn.com
Train from Nürnberg Hbf to Frankfurt(Main)Hbf
Ave. Duration
2 h 4 min
Frequency
Hourly
Estimated price
$50 - $75
Website
bahn.de
Train from Frankfurt(Main)Hbf to Mannheim Hbf
Ave. Duration
37 min
Frequency
Every 30 minutes
Estimated price
$14 - $21
Website
bahn.de
Train from Frankfurt(M) Flughafen Fernbf to Mannheim Hbf
Ave. Duration
31 min
Frequency
Hourly
Estimated price
$22 - $35
Website
bahn.de
Train from Siegburg/Bonn to Mannheim Hbf
Ave. Duration
1 h 14 min
Frequency
Hourly
Estimated price
$45 - $70
Website
bahn.de
TGV
Phone
0033 892 353535
Website
tgv.com
Train from Frankfurt(Main)Hbf to Mannheim Hbf
Ave. Duration
39 min
Frequency
4 times a day
Estimated price
$14 - $16
Website
en.oui.sncf
2nd Class
$14 - $16
1st Class
$18 - $28
Bus operators
FlixBus
Phone
+49 1807 123 99 123
Email
info@flixbus.de
Website
flixbus.de
Bus from Prague, Prague Anděl to Mannheim, Mannheim ZOB
Ave. Duration
7 h 10 min
Frequency
Twice daily
Estimated price
$30 - $55
Website
flixbus.co.uk
Bus from Prague, Prague Zličín to Plzeň, Pilsen
Ave. Duration
1 h
Frequency
Every 2 hours
Estimated price
$4 - $8
Website
flixbus.co.uk
RegioJet
Phone
+420 542 42 42 42
Email
info@regiojet.cz
Website
regiojet.sk
Bus from Praha, ÚAN Florenc to Mannheim, ZOB Heinrich von Stephan Str. 6
Ave. Duration
6 h 30 min
Frequency
Once daily
Estimated price
$18 - $23
Schedules at
regiojet.sk
Bus from Praha, ÚAN Florenc to Drážďany, Letiště
Ave. Duration
2 h 20 min
Frequency
Every 4 hours
Estimated price
$5 - $8
Schedules at
regiojet.sk
Leo Express s.r.o.
Phone
+420 220 311 700
Email
info@le.cz
Website
leoexpress.com
Bus from Praha Zličín to Plzeň CAN
Ave. Duration
1 h
Frequency
Every 4 hours
Estimated price
$4 - $7
Schedules at
leoexpress.com
Economy
$4 - $7
Eurolines DE
Phone
+49 6196 2078-501
Email
service@eurolines.de
Website
eurolines.de
Bus from Plzen to Heidelberg Hbf
Ave. Duration
5 h 45 min
Frequency
3 times a week
Estimated price
$50 - $70
Website
eurolines.de

Want to know more about travelling around Germany

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Questions & Answers

The distance between Prague and Mannheim is 432 km. The road distance is 513 km.

The cheapest way to get from Prague to Mannheim is to bus which costs 390 Kč - 1 100 Kč and takes 7 h 10 min.

The quickest way to get from Prague to Mannheim is to fly and train which takes 4 h 24 min and costs 1 700 Kč - 6 000 Kč.

Yes, there is a direct train departing from Praha hl.n. (Autobusová St. Wilsonova) and arriving at Mannheim Hbf (Busbahnhof). Services depart three times a day. The journey takes approximately 7 h 15 min.

Yes, there is a direct bus departing from Prague, Prague Anděl and arriving at Mannheim, Mannheim ZOB. Services depart twice daily, and operate every day. The journey takes approximately 7 h 10 min.

It takes approximately 6 h 55 min to get from Prague to Mannheim, including transfers.