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How to get fromPrague to Mannheimby bus, train, night train, car or plane

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There are 10 ways to get from Prague to Mannheim by bus, train, night train, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Prague to Mannheim central bus stationbus bus N1309 / ...
    6h 20m
    €27–50
  2. Train via Dresden

    1. Take the train from Praha-Holesovice to Dresden Hbftrain train Rj
    2. Take the train from Dresden Hauptbahnhof to Frankfurttrain train 50
    3. Take the train from Frankfurt to Mannheim, Hauptbahnhoftrain train 20 / ...
    8h 20m
    €56–160
  3. Night train

    1. Take the night train from Praha Hlavni Nadrazi to Mannheim Hbfnighttrain night train En
    9h 49m
    €140–200
  4. Drive 512.2 km

    1. Drive from Prague to Mannheimcar car 512.2 km
    4h 26m
    €77–111
  5. Bus via Heidelberg, Hauptbahnhof

    1. Take the bus from Prague - Florenc Main Bus Terminal to Heidelbergbus bus BlaBlaCar Bus
    7h 42m
    €42–57
  6. Train

    1. Take the train from Praha Hlavni Nadrazi to Mannheim Hbftrain train Ec
    9h 49m
    €120–170
  7. Fly Václav Havel Airport Prague to Frankfurt, train

    1. Fly from Václav Havel Airport Prague (PRG) to Frankfurt (FRA)plane plane PRG - FRA
    2. Take the train from Frankfurt to Mannheim, Hauptbahnhoftrain train
    4h 22m
    €77–194
  8. Train to Dresden Airport, fly to Frankfurt, train

    1. Take the train from Praha-Holesovice to Dresden Hbftrain train
    2. Fly from Dresden Airport (DRS) to Frankfurt (FRA)plane plane DRS - FRA
    3. Take the train from Frankfurt to Mannheim, Hauptbahnhoftrain train
    5h 48m
    €158–370
  9. Fly Václav Havel Airport Prague to Stuttgart Airport, train

    1. Fly from Václav Havel Airport Prague (PRG) to Stuttgart Airport (STR)plane plane PRG - STR
    2. Take the train from Hauptbahnhof to Mannheim, Hauptbahnhoftrain train
    6h 39m
    €110–265
  10. Fly Václav Havel Airport Prague to Munich International Airport, train

    1. Fly from Václav Havel Airport Prague (PRG) to Munich International Airport (MUC)plane plane PRG - MUC
    2. Take the train from Flughafen München to Hauptbahnhoftrain train
    3. Take the train from München Hbf to Mannheim, Hauptbahnhoftrain train
    6h 21m
    €117–399

Prague to Mannheim by bus

Calendar21Weekly Buses
Duration6h 20mAverage Duration
Ticket€27Cheapest Price
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Questions & Answers

What companies run services between Prague, Czechia and Mannheim, Germany?

FlixBus operates a bus from Prague to Mannheim central bus station 3 times a day. Tickets cost €27–50 and the journey takes 6h 20m. Alternatively, you can take a train from Praha-Holesovice to Mannheim, Hauptbahnhof via Dresden Hauptbahnhof and Frankfurt in around 8h 20m.

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Train operators
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