There are 10 ways to get from Prague to Mannheim by bus, train, night train, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Prague to Mannheim central bus stationbus N1309 / ...
6h 20m€27–50Train via Dresden
- Take the train from Praha-Holesovice to Dresden Hbftrain Rj
- Take the train from Dresden Hauptbahnhof to Frankfurttrain 50
- Take the train from Frankfurt to Mannheim, Hauptbahnhoftrain 20 / ...
8h 20m€56–160Night train
- Take the night train from Praha Hlavni Nadrazi to Mannheim Hbfnighttrain En
9h 49m€140–200Drive 512.2 km
- Drive from Prague to Mannheimcar 512.2 km
4h 26m€77–111Bus via Heidelberg, Hauptbahnhof
- Take the bus from Prague - Florenc Main Bus Terminal to Heidelbergbus BlaBlaCar Bus
7h 42m€42–57Train
- Take the train from Praha Hlavni Nadrazi to Mannheim Hbftrain Ec
9h 49m€120–170Fly Václav Havel Airport Prague to Frankfurt, train
- Fly from Václav Havel Airport Prague (PRG) to Frankfurt (FRA)plane PRG - FRA
- Take the train from Frankfurt to Mannheim, Hauptbahnhoftrain
4h 22m€77–194Train to Dresden Airport, fly to Frankfurt, train
- Take the train from Praha-Holesovice to Dresden Hbftrain
- Fly from Dresden Airport (DRS) to Frankfurt (FRA)plane DRS - FRA
- Take the train from Frankfurt to Mannheim, Hauptbahnhoftrain
5h 48m€158–370Fly Václav Havel Airport Prague to Stuttgart Airport, train
- Fly from Václav Havel Airport Prague (PRG) to Stuttgart Airport (STR)plane PRG - STR
- Take the train from Hauptbahnhof to Mannheim, Hauptbahnhoftrain
6h 39m€110–265Fly Václav Havel Airport Prague to Munich International Airport, train
- Fly from Václav Havel Airport Prague (PRG) to Munich International Airport (MUC)plane PRG - MUC
- Take the train from Flughafen München to Hauptbahnhoftrain
- Take the train from München Hbf to Mannheim, Hauptbahnhoftrain
6h 21m€117–399
Prague to Mannheim by bus
Questions & Answers
The cheapest way to get from Prague to Mannheim is to bus which costs €27 - €50 and takes 6h 20m.
The fastest way to get from Prague to Mannheim is to fly and train which takes 4h 22m and costs €75 - €200.
Yes, there is a direct bus departing from Prague and arriving at Mannheim central bus station station. Services depart three times a day, and operate every day. The journey takes approximately 6h 20m.
Yes, there is an overnight train departing from Praha Hlavni Nadrazi and arriving at Mannheim Hbf. This train operates every day. The journey takes approximately 9h 49m.
The distance between Prague and Mannheim is 512 km. The road distance is 512.2 km.
The best way to get from Prague to Mannheim without a car is to bus which takes 6h 20m and costs €27 - €50.
The bus from Prague to Mannheim central bus station takes 6h 20m including transfers and departs three times a day.
Prague to Mannheim bus services, operated by FlixBus, depart from Prague station.
Prague to Mannheim train services, operated by České dráhy (ČD), depart from Praha-Holesovice station.
The best way to get from Prague to Mannheim is to bus which takes 6h 20m and costs €27 - €50. Alternatively, you can train via Dresden, which costs €55 - €160 and takes 8h 20m.
What companies run services between Prague, Czechia and Mannheim, Germany?
FlixBus operates a bus from Prague to Mannheim central bus station 3 times a day. Tickets cost €27–50 and the journey takes 6h 20m. Alternatively, you can take a train from Praha-Holesovice to Mannheim, Hauptbahnhof via Dresden Hauptbahnhof and Frankfurt in around 8h 20m.
- Website
- lufthansa.com
Flights from Václav Havel Airport Prague to Frankfurt
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- €60–250
Flights from Václav Havel Airport Prague to Frankfurt via Munich International Airport
- Ave. Duration
- 2h 45m
- When
- Monday, Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- €60–170
Flights from Dresden Airport to Frankfurt
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- €120–270
Flights from Dresden Airport to Frankfurt via Munich International Airport
- Ave. Duration
- 2h 52m
- When
- Monday to Saturday
- Estimated price
- €120–270
Flights from Václav Havel Airport Prague to Stuttgart Airport via Munich International Airport
- Ave. Duration
- 2h 40m
- When
- Every day
- Estimated price
- €80–320
Flights from Václav Havel Airport Prague to Stuttgart Airport via Frankfurt
- Ave. Duration
- 3h 21m
- When
- Every day
- Estimated price
- €80–340
Flights from Václav Havel Airport Prague to Munich International Airport
- Ave. Duration
- 55 min
- When
- Every day
- Estimated price
- €80–140
- Website
- condor.com
Flights from Václav Havel Airport Prague to Frankfurt
- Ave. Duration
- 1h 1m
- When
- Every day
- Estimated price
- €65–140
- Website
- swiss.com
Flights from Václav Havel Airport Prague to Stuttgart Airport via Zurich
- Ave. Duration
- 3h 35m
- When
- Every day
- Estimated price
- €80–330
- Website
- klm.com
Flights from Václav Havel Airport Prague to Stuttgart Airport via Amsterdam Schiphol
- Ave. Duration
- 4h 58m
- When
- Every day
- Estimated price
- €60–350
- Website
- airdolomiti.it
Flights from Václav Havel Airport Prague to Frankfurt
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- €70–250
- Website
- austrian.com
Flights from Václav Havel Airport Prague to Stuttgart Airport via Vienna
- Ave. Duration
- 3h 47m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €80–330
- Phone
- +420 221 111 122
- info@cd.cz
- Website
- cd.cz
Train from Praha-Holesovice to Dresden Hbf
- Ave. Duration
- 2h 9m
- Frequency
- Every 4 hours
- Estimated price
- €20–45
- Website
- https://www.cd.cz/en/default.htm
Train from Praha-Holesovice to Dresden Hbf
- Ave. Duration
- 2h 9m
- Frequency
- Twice daily
- Estimated price
- €30–45
- Website
- https://www.oebb.at/en/reiseplanung-services/im-zug/unsere-zuege/railjet
- *
- €30–45
- Phone
- +43 5 1717
- Website
- oebb.at
Train from Praha-Holesovice to Dresden Hbf
- Ave. Duration
- 2h 18m
- Frequency
- 6 times a week
- Estimated price
- €35–50
- Website
- https://www.oebb.at/en/reiseplanung-services/im-zug/unsere-zuege/eurocity-intercity
- Website
- https://shop.oebbtickets.at/en/ticket
Train from Praha Hlavni Nadrazi to Mannheim Hbf
- Ave. Duration
- 9h 49m
- Frequency
- 5 times a week
- Estimated price
- €120–170
- Website
- https://www.oebb.at/en/reiseplanung-services/im-zug/unsere-zuege/eurocity-intercity
- Website
- https://shop.oebbtickets.at/en/ticket
- Phone
- +49 30 311 682904
- Website
- bahn.de
Train from Dresden Hauptbahnhof to Frankfurt
- Ave. Duration
- 4h 26m
- Frequency
- Every 3 hours
- Estimated price
- €28–80
- Website
- https://int.bahn.de/en
Train from Frankfurt to Mannheim, Hauptbahnhof
- Ave. Duration
- 37 min
- Frequency
- Every 30 minutes
- Estimated price
- €7–30
- Website
- https://int.bahn.de/en
Train from Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 38 min
- Frequency
- Hourly
- Estimated price
- €16–40
- Website
- https://int.bahn.de/en
Train from München Hbf to Mannheim, Hauptbahnhof
- Ave. Duration
- 2h 45m
- Frequency
- Hourly
- Estimated price
- €20–75
- Website
- https://int.bahn.de/en
- Phone
- +49 30 2970
- Website
- bahn.de
Train from Frankfurt to Mannheim, Hauptbahnhof
- Ave. Duration
- 1h 1m
- Frequency
- Every 30 minutes
- Estimated price
- €14–21
- Website
- https://int.bahn.de/en
Train from Flughafen München to Hauptbahnhof
- Ave. Duration
- 44 min
- Frequency
- Every 15 minutes
- Estimated price
- €10–15
- Website
- https://int.bahn.de/en
- Phone
- 0621 8301200
- Website
- suewex.de
Train from Frankfurt to Mannheim, Hauptbahnhof
- Ave. Duration
- 1h 29m
- Frequency
- Twice daily
- Estimated price
- €15–22
- Schedules at
- suewex.de
Night train from Praha Hlavni Nadrazi to Mannheim Hbf
- Ave. Duration
- 9h 49m
- Frequency
- Once daily
- Estimated price
- €140–200
- Website
- https://www.oebb.at/en/
- Phone
- +31 30 751 5155
- Website
- ns.nl
Train from Frankfurt to Mannheim, Hauptbahnhof
- Ave. Duration
- 1h 23m
- Frequency
- 4 times a day
- Estimated price
- €12–40
- Website
- https://www.ns.nl/en
- 2nd Class
- €12–19
- 1st Class
- €23–40
Train from Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 38 min
- Frequency
- Once daily
- Estimated price
- €18–60
- Website
- https://www.ns.nl/en
- 2nd Class
- €18–27
- 1st Class
- €30–60
Train from München Hbf to Mannheim, Hauptbahnhof
- Ave. Duration
- 2h 44m
- Frequency
- Once daily
- Estimated price
- €50–180
- Website
- https://www.ns.nl/en
- 2nd Class
- €50–80
- 1st Class
- €110–180
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Prague to Mannheim central bus station
- Ave. Duration
- 6h 20m
- Frequency
- 3 times a day
- Estimated price
- €27–50
- Website
- https://www.flixbus.co.uk
- Phone
- +3-389-268-0068
- Website
- blablacar.co.uk
Bus from Prague - Florenc Main Bus Terminal to Heidelberg
- Ave. Duration
- 6h 55m
- Frequency
- Twice a week
- Estimated price
- €35–55
- Website
- https://www.blablacar.co.uk/bus
Want to know more about travelling around Germany
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More Questions & Answers
Prague to Mannheim bus services, operated by FlixBus, arrive at Mannheim central bus station.
Prague to Mannheim train services, operated by České dráhy (ČD), arrive at Dresden Hbf station.
Yes, the driving distance between Prague to Mannheim is 512 km. It takes approximately 4h 26m to drive from Prague to Mannheim.
Book your Prague to Mannheim train tickets online with Omio.
Book your Prague to Mannheim bus tickets online with Omio and FlixBus.
There are 1402+ hotels available in Mannheim.



















































