There are 10 ways to get from Prague to Mannheim by bus, train, night train, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Prague to Mannheim central bus stationN1309 / ...
6h 20m€30–80Bus via Heidelberg, Hauptbahnhof
cheapest- Take the bus from Prague - Florenc Main Bus Terminal to HeidelbergBlaBlaCar Bus
7h 43m€25–52Train via Dresden
- Take the train from Praha Hlavni Nadrazi to Dresden HbfEc
- Take the train from Dresden Hauptbahnhof to Frankfurt50
- Take the train from Frankfurt to Mannheim, Hauptbahnhof20 / ...
8h 37m€55–159Night train
- Take the night train from Praha Hlavni Nadrazi to Mannheim HbfEn
9h 49m€140–200Drive 512.8 km
- Drive from Prague to Mannheim512.8 km
4h 24m€78–112Train
- Take the train from Praha Hlavni Nadrazi to Mannheim HbfEc
9h 49m€120–170Fly Václav Havel Airport Prague to Frankfurt, train
- Fly from Václav Havel Airport Prague (PRG) to Frankfurt (FRA)PRG - FRA
- Take the train from Frankfurt to Mannheim, Hauptbahnhof
4h 22m€73–182Train to Dresden Airport, fly to Frankfurt, train
- Take the train from Praha Hlavni Nadrazi to Dresden Hbf
- Fly from Dresden Airport (DRS) to Frankfurt (FRA)DRS - FRA
- Take the train from Frankfurt to Mannheim, Hauptbahnhof
6h€147–329Fly Václav Havel Airport Prague to Stuttgart Airport, train
- Fly from Václav Havel Airport Prague (PRG) to Stuttgart Airport (STR)PRG - STR
- Take the train from Hauptbahnhof to Mannheim, Hauptbahnhof
6h 36m€116–273Fly Václav Havel Airport Prague to Munich International Airport, train
- Fly from Václav Havel Airport Prague (PRG) to Munich International Airport (MUC)PRG - MUC
- Take the train from Flughafen München to Pasing
- Take the train from Pasing to Mannheim, Hauptbahnhof
6h 41m€146–302
Prague to Mannheim by bus
Questions & Answers
The cheapest way to get from Prague to Mannheim is to bus via Heidelberg, Hauptbahnhof which costs €25 - €55 and takes 7h 43m.
The fastest way to get from Prague to Mannheim is to fly and train which takes 4h 22m and costs €70 - €190.
Yes, there is a direct bus departing from Prague and arriving at Mannheim central bus station station. Services depart three times a day, and operate every day. The journey takes approximately 6h 20m.
Yes, there is an overnight train departing from Praha Hlavni Nadrazi and arriving at Mannheim Hbf. This train operates every day. The journey takes approximately 9h 49m.
The distance between Prague and Mannheim is 512 km. The road distance is 512.8 km.
The best way to get from Prague to Mannheim without a car is to bus which takes 6h 20m and costs €30 - €80.
The bus from Prague to Mannheim central bus station takes 6h 20m including transfers and departs three times a day.
Prague to Mannheim bus services, operated by FlixBus, depart from Prague station.
Prague to Mannheim train services, operated by ÖBB EuroCity, depart from Praha Hlavni Nadrazi station.
The best way to get from Prague to Mannheim is to bus which takes 6h 20m and costs €30 - €80. Alternatively, you can train via Dresden, which costs €55 - €160 and takes 8h 37m.
What companies run services between Prague, Czechia and Mannheim, Germany?
FlixBus operates a bus from Prague to Mannheim central bus station 3 times a day. Tickets cost €30–80 and the journey takes 6h 20m. Alternatively, you can take a train from Praha Hlavni Nadrazi to Mannheim, Hauptbahnhof via Dresden Hauptbahnhof and Frankfurt in around 8h 37m.
- Website
- lufthansa.com
Flights from Václav Havel Airport Prague to Frankfurt
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- €80–280
Flights from Václav Havel Airport Prague to Frankfurt via Munich International Airport
- Ave. Duration
- 2h 45m
- When
- Monday, Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- €80–170
Flights from Dresden Airport to Frankfurt
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- €120–290
Flights from Dresden Airport to Frankfurt via Munich International Airport
- Ave. Duration
- 2h 50m
- When
- Monday, Wednesday, and Friday
- Estimated price
- €120–290
Flights from Václav Havel Airport Prague to Stuttgart Airport via Munich International Airport
- Ave. Duration
- 2h 40m
- When
- Every day
- Estimated price
- €80–320
Flights from Václav Havel Airport Prague to Stuttgart Airport via Frankfurt
- Ave. Duration
- 4h 21m
- When
- Every day
- Estimated price
- €80–360
Flights from Václav Havel Airport Prague to Munich International Airport
- Ave. Duration
- 55 min
- When
- Every day
- Estimated price
- €75–190
- Website
- condor.com
Flights from Václav Havel Airport Prague to Frankfurt
- Ave. Duration
- 1h 1m
- When
- Every day
- Estimated price
- €60–140
- Website
- klm.com
Flights from Václav Havel Airport Prague to Stuttgart Airport via Amsterdam Schiphol
- Ave. Duration
- 5h 12m
- When
- Every day
- Estimated price
- €60–330
- Website
- swiss.com
Flights from Václav Havel Airport Prague to Stuttgart Airport via Zurich
- Ave. Duration
- 3h 33m
- When
- Every day
- Estimated price
- €80–320
- Website
- airdolomiti.it
Flights from Václav Havel Airport Prague to Frankfurt
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- €85–280
- Website
- austrian.com
Flights from Václav Havel Airport Prague to Stuttgart Airport via Vienna
- Ave. Duration
- 3h 47m
- When
- Thursday, Friday, and Sunday
- Estimated price
- €75–330
- Phone
- +43 5 1717
- Website
- oebb.at
Train from Praha Hlavni Nadrazi to Dresden Hbf
- Ave. Duration
- 2h 22m
- Frequency
- 5 times a day
- Estimated price
- €35–55
- Website
- https://www.oebb.at/en/reiseplanung-services/im-zug/unsere-zuege/eurocity-intercity
- Website
- https://shop.oebbtickets.at/en/ticket
Train from Praha Hlavni Nadrazi to Mannheim Hbf
- Ave. Duration
- 9h 49m
- Frequency
- 5 times a week
- Estimated price
- €120–170
- Website
- https://www.oebb.at/en/reiseplanung-services/im-zug/unsere-zuege/eurocity-intercity
- Website
- https://shop.oebbtickets.at/en/ticket
Train from Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 43 min
- Frequency
- Once daily
- Estimated price
- €26–35
- Website
- https://www.oebb.at/en/reiseplanung-services/im-zug/unsere-zuege/eurocity-intercity
- Website
- https://shop.oebbtickets.at/en/ticket
- Phone
- +420 221 111 122
- info@cd.cz
- Website
- cd.cz
Train from Praha Hlavni Nadrazi to Dresden Hbf
- Ave. Duration
- 2h 19m
- Frequency
- 5 times a day
- Estimated price
- €11–24
- Website
- https://www.cd.cz/en/default.htm
- 2nd Class
- €11–16
- 1st Class
- €18–24
- Business
- €19–21
- Phone
- +36 (1) 3 49 49 49
- info@mavcsoport.hu
- Website
- jegy.mav.hu
Train from Praha Hlavni Nadrazi to Dresden Hbf
- Ave. Duration
- 2h 17m
- Frequency
- Once daily
- Estimated price
- €8–10
- Website
- https://jegy.mav.hu/
- Phone
- +49 30 311 682904
- Website
- bahn.de
Train from Dresden Hauptbahnhof to Frankfurt
- Ave. Duration
- 4h 26m
- Frequency
- Every 3 hours
- Estimated price
- €40–120
- Website
- https://int.bahn.de/en
Train from Frankfurt to Mannheim, Hauptbahnhof
- Ave. Duration
- 37 min
- Frequency
- Every 30 minutes
- Estimated price
- €7–30
- Website
- https://int.bahn.de/en
Train from Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 38 min
- Frequency
- Hourly
- Estimated price
- €18–50
- Website
- https://int.bahn.de/en
Train from Pasing to Mannheim, Hauptbahnhof
- Ave. Duration
- 2h 45m
- Frequency
- Hourly
- Estimated price
- €45–95
- Website
- https://int.bahn.de/en
- Phone
- +49 30 2970
- Website
- bahn.de
Train from Frankfurt to Mannheim, Hauptbahnhof
- Ave. Duration
- 1h 11m
- Frequency
- Every 3 hours
- Estimated price
- €14–21
- Website
- https://int.bahn.de/en
Train from Flughafen München to Pasing
- Ave. Duration
- 49 min
- Frequency
- Every 20 minutes
- Estimated price
- €10–15
- Website
- https://int.bahn.de/en
- Phone
- 0621 8301200
- Website
- suewex.de
Train from Frankfurt to Mannheim, Hauptbahnhof
- Ave. Duration
- 1h 44m
- Frequency
- Twice daily
- Estimated price
- €15–22
- Schedules at
- suewex.de
Night train from Praha Hlavni Nadrazi to Mannheim Hbf
- Ave. Duration
- 9h 49m
- Frequency
- Once daily
- Estimated price
- €140–200
- Website
- https://www.oebb.at/en/
- Phone
- +31 30 751 5155
- Website
- ns.nl
Train from Frankfurt to Mannheim, Hauptbahnhof
- Ave. Duration
- 1h 23m
- Frequency
- 3 times a day
- Estimated price
- €12–40
- Website
- https://www.ns.nl/en
- 2nd Class
- €12–19
- 1st Class
- €23–40
Train from Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 38 min
- Frequency
- Once daily
- Estimated price
- €18–60
- Website
- https://www.ns.nl/en
- 2nd Class
- €18–27
- 1st Class
- €30–60
Train from Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 1h 3m
- Frequency
- Twice a week
- Estimated price
- €20–35
- Website
- https://www.oebb.at/en/reiseplanung-services/im-zug/unsere-zuege/railjet
- *
- €20–30
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Prague to Mannheim central bus station
- Ave. Duration
- 6h 20m
- Frequency
- 3 times a day
- Estimated price
- €30–80
- Website
- https://www.flixbus.co.uk
- Phone
- +3-389-268-0068
- Website
- blablacar.co.uk
Bus from Prague - Florenc Main Bus Terminal to Heidelberg
- Ave. Duration
- 6h 55m
- Frequency
- Twice a week
- Estimated price
- €20–45
- Website
- https://www.blablacar.co.uk/bus
Want to know more about travelling around Germany
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More Questions & Answers
Prague to Mannheim bus services, operated by FlixBus, arrive at Mannheim central bus station.
Prague to Mannheim train services, operated by ÖBB EuroCity, arrive at Dresden Hbf station.
Yes, the driving distance between Prague to Mannheim is 513 km. It takes approximately 4h 24m to drive from Prague to Mannheim.
Book your Prague to Mannheim train tickets online with Omio.
Book your Prague to Mannheim bus tickets online with Omio and FlixBus.
There are 1405+ hotels available in Mannheim.


























































