The average train between Prague and Italy takes 21h 35m and the fastest train takes 16h 8m. The train service runs several times per day from Prague to Italy. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 3 times a day between Prague and Italy. The earliest departure is at 5:35 AM in the morning, and the last departure from Prague is at 5:35 PM which arrives into Italy at 5:40 PM. All services require a transfer at Muenchen Hbf and take an average of 21h 35m. The schedules shown below are for the next available departures.


16h 8m • 2 changes
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25h 5m • 2 changes
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24h 5m • 2 changes


16h 8m • 2 changes
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25h 5m • 2 changes
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26h 20m • 2 changes


16h 8m • 2 changes
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25h 5m • 2 changes
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24h 5m • 2 changes


16h 8m • 2 changes
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24h 5m • 2 changes


16h 8m • 2 changes
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25h 5m • 2 changes
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24h 5m • 2 changes
Want to know about travelling from Prague to Italy? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Prague to Italy. However, there are services departing from Prague station and arriving at Italy station via Muenchen Hbf. The journey, including transfers, takes approximately 21h 35m.
Prague to Italy train services, operated by ÖBB EuroCity, depart from Praha Hlavni Nadrazi station.
Prague to Italy train services, operated by ÖBB EuroCity, arrive at Roma Termini station.
Book your Prague to Italy train tickets online with ÖBB EuroCity, Deutsche Bahn Intercity (DB IC) and ItaloTreno.
The distance between Prague and Italy is 839.1 km. The road distance is 1,329 km.
You can take a train from Praha Hlavni Nadrazi to Roma Termini via Muenchen Hbf, München Hbf, and Verona Porta Nuova in around 16h 32m.