The average train between Prague and Leipzig takes 4h 5m and the fastest train takes 3h 34m. The train service runs several times per day from Prague to Leipzig. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Prague and Leipzig. The earliest departure is at 6:41 AM in the morning, and the last departure from Prague is at 8:57 PM which arrives into Leipzig at 2:52 AM. All services require a transfer, and take on average 4h 5m. The schedules shown below are for the next available departures.

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3h 34m • 1 changeWant to know about travelling from Prague to Leipzig? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Prague to Leipzig. However, there are services departing from Prague station and arriving at Leipzig station via Dresden Hbf. The journey, including transfers, takes approximately 4h 5m.
Prague to Leipzig train services, operated by Danish Railways (DSB), depart from Praha-Holesovice station.
Prague to Leipzig train services, operated by Danish Railways (DSB), arrive at Leipzig Hbf station.
Book your Prague to Leipzig train tickets online with Danish Railways (DSB), Deutsche Bahn Intercity (DB IC) and 5 other operators.
The distance between Prague and Leipzig is 200.5 km. The road distance is 303 km.
You can take a train from Praha-Holesovice to Leipzig Hbf via Dresden Hauptbahnhof in around 3h 35m.