The average train between Prague and Leipzig takes 4h 10m and the fastest train takes 3h 34m. The train service runs several times per day from Prague to Leipzig. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Prague and Leipzig. The earliest departure is at 6:41 AM in the morning, and the last departure from Prague is at 8:57 PM which arrives into Leipzig at 2:52 AM. All services require a transfer, and take on average 4h 10m. The schedules shown below are for the next available departures.

3h 34m • 1 change
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3h 37m • 1 change
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3h 37m • 1 changeWant to know about travelling from Prague to Leipzig? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Prague to Leipzig. However, there are services departing from Praha-Holesovice station and arriving at Leipzig Hbf station via Dresden Hbf station. The journey, including transfers, takes approximately 4h 10m.
Prague to Leipzig train services, operated by České dráhy (ČD), depart from Praha-Holesovice station.
Prague to Leipzig train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Leipzig Hbf station.
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The distance between Prague and Leipzig is 200.5 km. The road distance is 236 km.
You can take a train from Praha-Holesovice to Leipzig Hbf via Dresden Hauptbahnhof in around 3h 35m.