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Portland to La Mesa trains

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Trip Overview

The average train between Portland and La Mesa takes 38h 48m and the fastest train takes 38h 42m. The train runs, on average, 5 times per week from Portland to La Mesa. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

38h 48m
Duration
1,326 mi
Distance
$863
Average price
5 times a week
Frequency

Portland to La Mesa train times

Trains run 5 times a week between Portland and La Mesa. The service departs Portland at 2:22 PM in the afternoon, which arrives into La Mesa at 05:04:00. All services require a transfer at Los Angeles and take an average of 38h 48m. The schedules shown below are for the next available departures.

Departing Monday, November 9, 2026

  •  → 

    Arrives +2 days

    AmtrakAmtrakSan Diego Metro Transit38h 42m • 2 changes

Departing Tuesday, November 10, 2026

  •  → 

    Arrives +2 days

    AmtrakAmtrakSan Diego Metro Transit38h 42m • 2 changes

Departing Wednesday, November 11, 2026

  •  → 

    Arrives +2 days

    AmtrakAmtrakSan Diego Metro Transit38h 42m • 2 changes

Departing Thursday, November 12, 2026

  •  → 

    Arrives +2 days

    AmtrakAmtrakSan Diego Metro Transit38h 57m • 2 changes

Departing Friday, November 13, 2026

  •  → 

    Arrives +2 days

    AmtrakAmtrakSan Diego Metro Transit38h 57m • 2 changes

Frequently asked questions

Want to know about travelling from Portland to La Mesa? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Portland to La Mesa.ExpandLaunch map view
  • Distance: 1,325.8 mi
  • Duration: 38h 48m

What companies run services between Portland, OR, USA and La Mesa, CA, USA?

You can take a train from Portland to 70th Street Station via Los Angeles, San Diego Old Town Transportation Center, and Old Town Station in around 35h 2m.

Operators