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How to get fromPortland to La Mesaby plane, tram, bus (Flixbus, Greyhound), train (Amtrak), car or train

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There are 5 ways to get from Portland to La Mesa by plane, tram, bus (Flixbus, Greyhound), train (Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Portland International Airport, tram

    best
    1. Fly from Portland International Airport (PDX) to San Diego International Airport (SAN)plane plane PDX - SAN
    2. Take the tram from Civic Center Station to La Mesa Blvd Stationtram tram
    5h 21m
    $167–873
  2. Bus

    cheapest
    1. Take the bus from Portland Curbside Bus Stop to Sacramento Bus Stationbus bus FlixBus N2111
    2. Take the bus from Sacramento Bus Station to San Diego Greyhound Bus Stopbus bus Greyhound US0831
    28h 39m
    $142–300
  3. Train (Amtrak)

    1. Take the train from Portland to Los Angelestrain train Coast Starlight
    2. Take the train from Los Angeles to San Diego Old Town Transportation Centertrain train Pacific Surfliner
    35h 5m
    $178–270
  4. Drive 1,085.7 mi

    1. Drive from Portland to La Mesacar car 1,085.7 mi
    18h 19m
    $199–287
  5. Train to Mahlon Sweet Field Airport, fly

    1. Take the train from Portland to Eugenetrain train
    2. Fly from Mahlon Sweet Field Airport (EUG) to San Diego International Airport (SAN)plane plane EUG - SAN
    7h 49m
    $163–749

Portland to La Mesa by bus

Calendar7Weekly Buses
Duration28h 39mAverage Duration
Ticket$142Cheapest Price
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Questions & Answers

What companies run services between Portland, OR, USA and La Mesa, CA, USA?

You can take a bus from Portland Curbside Bus Stop to University Av & Allison Av via Sacramento Bus Station, San Diego Greyhound Bus Stop, Old Town Transit Center, and University Av & College Av in around 28h 39m. Alternatively, you can take a train from Portland to 70th Street Station via Los Angeles, San Diego Old Town Transportation Center, and Old Town Station in around 35h 5m.

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