There are 5 ways to get from Portland to La Mesa by plane, tram, bus (Flixbus, Greyhound), train (Amtrak), car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Portland International Airport, tram
best- Fly from Portland International Airport (PDX) to San Diego International Airport (SAN)plane PDX - SAN
- Take the tram from Civic Center Station to La Mesa Blvd Stationtram
5h 21m$167–873Bus
cheapest- Take the bus from Portland Curbside Bus Stop to Sacramento Bus Stationbus FlixBus N2111
- Take the bus from Sacramento Bus Station to San Diego Greyhound Bus Stopbus Greyhound US0831
28h 39m$142–300Train (Amtrak)
- Take the train from Portland to Los Angelestrain Coast Starlight
- Take the train from Los Angeles to San Diego Old Town Transportation Centertrain Pacific Surfliner
35h 5m$178–270Drive 1,085.7 mi
- Drive from Portland to La Mesacar 1,085.7 mi
18h 19m$199–287Train to Mahlon Sweet Field Airport, fly
- Take the train from Portland to Eugenetrain
- Fly from Mahlon Sweet Field Airport (EUG) to San Diego International Airport (SAN)plane EUG - SAN
7h 49m$163–749
Portland to La Mesa by bus
Questions & Answers
The cheapest way to get from Portland to La Mesa is to bus which costs $140 - $300 and takes 28h 39m.
The fastest way to get from Portland to La Mesa is to fly and tram which takes 5h 21m and costs $160 - $900.
No, there is no direct bus from Portland to La Mesa. However, there are services departing from Portland Curbside Bus Stop and arriving at University Av & Allison Av via Sacramento Bus Station, Old Town Transit Center and University Av & College Av. The journey, including transfers, takes approximately 28h 39m.
No, there is no direct train from Portland to La Mesa station. However, there are services departing from Portland and arriving at 70th Street Station via Los Angeles and Old Town Station. The journey, including transfers, takes approximately 35h 5m.
The distance between Portland and La Mesa is 968 miles. The road distance is 1092 miles.
The best way to get from Portland to La Mesa without a car is to bus which takes 28h 39m and costs $140 - $300.
It takes approximately 5h 21m to get from Portland to La Mesa, including transfers.
Portland to La Mesa bus services, operated by Flixbus USA, depart from Portland Curbside Bus Stop station.
Portland to La Mesa train services, operated by Amtrak, depart from Portland station.
The best way to get from Portland to La Mesa is to bus which takes 28h 39m and costs $140 - $300. Alternatively, you can train, which costs $170 - $270 and takes 35h 5m.
What companies run services between Portland, OR, USA and La Mesa, CA, USA?
You can take a bus from Portland Curbside Bus Stop to University Av & Allison Av via Sacramento Bus Station, San Diego Greyhound Bus Stop, Old Town Transit Center, and University Av & College Av in around 28h 39m. Alternatively, you can take a train from Portland to 70th Street Station via Los Angeles, San Diego Old Town Transportation Center, and Old Town Station in around 35h 5m.
- Website
- southwest.com
Flights from Portland International Airport to San Diego International Airport
- Ave. Duration
- 2h 25m
- When
- Monday, Thursday, and Friday
- Estimated price
- $160–850
Flights from Portland International Airport to San Diego International Airport via Sacramento
- Ave. Duration
- 4h 1m
- When
- Monday, Tuesday, Thursday, Friday, and Sunday
- Estimated price
- $160–850
Flights from Portland International Airport to San Diego International Airport via San Jose
- Ave. Duration
- 4h 11m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $160–850
Flights from Portland International Airport to San Diego International Airport via Oakland
- Ave. Duration
- 4h 5m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $170–850
Flights from Mahlon Sweet Field Airport to San Diego International Airport
- Ave. Duration
- 2h 30m
- When
- Monday, Thursday, and Friday
- Estimated price
- $110–650
Flights from Mahlon Sweet Field Airport to San Diego International Airport via San Jose
- Ave. Duration
- 4h
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $120–650
Flights from Mahlon Sweet Field Airport to San Diego International Airport via Las Vegas
- Ave. Duration
- 5h
- When
- Tuesday and Saturday
- Estimated price
- $120–650
Flights from Mahlon Sweet Field Airport to San Diego International Airport via Sacramento
- Ave. Duration
- 4h 37m
- When
- Tuesday, Wednesday, Thursday, Saturday, and Sunday
- Estimated price
- $120–650
Flights from Mahlon Sweet Field Airport to San Diego International Airport via Oakland
- Ave. Duration
- 5h 35m
- When
- Monday, Tuesday, Thursday, and Sunday
- Estimated price
- $120–650
- Website
- alaskaair.com
Flights from Portland International Airport to San Diego International Airport
- Ave. Duration
- 2h 37m
- When
- Every day
- Estimated price
- $160–850
Flights from Portland International Airport to San Diego International Airport via Medford
- Ave. Duration
- 4h 27m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $160–850
Flights from Portland International Airport to San Diego International Airport via Reno
- Ave. Duration
- 4h 31m
- When
- Saturday
- Estimated price
- $160–850
Flights from Mahlon Sweet Field Airport to San Diego International Airport
- Ave. Duration
- 2h 31m
- When
- Every day
- Estimated price
- $110–650
Flights from Mahlon Sweet Field Airport to San Diego International Airport via Portland International Airport
- Ave. Duration
- 4h 27m
- When
- Every day
- Estimated price
- $130–700
- Website
- united.com
Flights from Mahlon Sweet Field Airport to San Diego International Airport via San Francisco
- Ave. Duration
- 4h 39m
- When
- Every day
- Estimated price
- $120–650
- Phone
- +1 619-233-3004
- Website
- sdmts.com
Tram from Civic Center Station to La Mesa Blvd Station
- Ave. Duration
- 39 min
- Frequency
- Every 20 minutes
- Estimated price
- $2–15
- Website
- https://www.sdmts.com
- Schedules at
- https://www.sdmts.com/getting-around/departures-and-schedules
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Portland to Los Angeles
- Ave. Duration
- 30h 49m
- Frequency
- Once daily
- Estimated price
- $140–220
- Website
- https://www.amtrak.com/home.html
Train from Los Angeles to San Diego Old Town Transportation Center
- Ave. Duration
- 2h 40m
- Frequency
- Every 2 hours
- Estimated price
- $30–40
- Website
- https://www.amtrak.com/home.html
Train from Portland to Eugene
- Ave. Duration
- 2h 38m
- Frequency
- 3 times a day
- Estimated price
- $19–40
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Portland Curbside Bus Stop to Sacramento Bus Station
- Ave. Duration
- 12h 5m
- Frequency
- Once daily
- Estimated price
- $65–120
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Portland Curbside Bus Stop to Sacramento Bus Station
- Ave. Duration
- 12h 40m
- Frequency
- Once daily
- Estimated price
- $65–100
- Website
- https://www.greyhound.com/
Bus from Sacramento Bus Station to San Diego Greyhound Bus Stop
- Ave. Duration
- 13h 55m
- Frequency
- Once daily
- Estimated price
- $70–170
- Website
- https://www.greyhound.com/
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More Questions & Answers
Portland to La Mesa bus services, operated by Flixbus USA, arrive at Sacramento Bus Station.
Portland to La Mesa train services, operated by Amtrak, arrive at Los Angeles station.
Yes, the driving distance between Portland to La Mesa is 1092 miles. It takes approximately 18h 19m to drive from Portland to La Mesa.
There are 1883+ hotels available in La Mesa.












