The average train between Poitiers and Lyon takes 6h 44m and the fastest train takes 4h 12m. The train service runs several times per day from Poitiers to Lyon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 3 times a day between Poitiers and Lyon. The earliest departure is at 5:18 AM in the morning, and the last departure from Poitiers is at 10:41 PM which arrives into Lyon at 9:30 AM. All services require a transfer, and take on average 6h 44m. The schedules shown below are for the next available departures.

5h 45m • 1 change

5h 51m • 1 change

7h 6m • 1 change
Arrives next day

10h 49m • 1 change

5h 45m • 1 change

6h 14m • 1 change

7h 6m • 1 change
Arrives next day

13h 28m • 1 change
Want to know about travelling from Poitiers to Lyon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Poitiers to Lyon. However, there are services departing from Poitiers station and arriving at Lyon station via St Pierre Des Corps. The journey, including transfers, takes approximately 6h 44m.
Poitiers to Lyon train services, operated by TGV inOui, depart from Poitiers station.
Poitiers to Lyon train services, operated by TGV inOui, arrive at Lyon Part Dieu station.
Book your Poitiers to Lyon train tickets online with TGV inOui and Société Nationale des Chemins de fer Français (SNCF).
The distance between Poitiers and Lyon is 358.9 km. The road distance is 567 km.
You can take a train from Poitiers to Lyon Part Dieu via Saint-Pierre-des-Corps in around 6h 51m.