The average train between Manosque and Lyon takes 5h 23m and the fastest train takes 3h 14m. The train service runs several times per day from Manosque to Lyon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 5 times a day between Manosque and Lyon. The earliest departure is at 6:25 AM in the morning, and the last departure from Manosque is at 8:31 PM which arrives into Lyon at 8:20 AM. All services require a transfer, and take on average 5h 23m. The schedules shown below are for the next available departures.

3h 29m • 1 change

4h 2m • 1 change

4h 52m • 1 change

4h 6m • 1 change

3h 29m • 1 change

4h 2m • 1 change

4h 52m • 1 change

4h 6m • 1 change

3h 29m • 1 change

4h 2m • 1 change

4h • 1 change

4h 6m • 1 change

3h 57m • 1 change

3h 46m • 1 change

4h 6m • 1 change

4h 42m • 1 change

3h 14m • 1 change

3h 57m • 1 change

3h 46m • 1 change

4h 6m • 1 change
Want to know about travelling from Manosque to Lyon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Manosque to Lyon. However, there are services departing from Manosque station and arriving at Lyon station via Marseille St Charles. The journey, including transfers, takes approximately 5h 23m.
Manosque to Lyon train services, operated by Société Nationale des Chemins de fer Français (SNCF), depart from Manosque Greoux Les Bains station.
Manosque to Lyon train services, operated by Société Nationale des Chemins de fer Français (SNCF), arrive at Lyon Part Dieu station.
Book your Manosque to Lyon train tickets online with Société Nationale des Chemins de fer Français (SNCF) and TGV inOui.
The distance between Manosque and Lyon is 226 km. The road distance is 416 km.
You can take a train from Manosque Greoux Les Bains to Lyon Part Dieu via Marseille St Charles in around 3h 49m.