The average train between Poissy and Lyon takes 2h 45m and the fastest train takes 2h 32m. There is a train service every few hours from Poissy to Lyon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Poissy and Lyon. The earliest departure is at 5:39 AM in the morning, and the last departure from Poissy is at 8:04 PM which arrives into Lyon at 11:10 PM. All services require a transfer, and take on average 2h 45m. The schedules shown below are for the next available departures.

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2h 46m • 1 changeWant to know about travelling from Poissy to Lyon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Poissy to Lyon. However, there are services departing from Poissy station and arriving at Lyon Part Dieu station via Paris Gare de Lyon station. The journey, including transfers, takes approximately 2h 45m.
Poissy to Lyon train services, operated by Réseau Express Régional (RER Paris), depart from Poissy station.
Poissy to Lyon train services, operated by TGV inOui, arrive at Lyon Part Dieu station.
The distance between Poissy and Lyon is 411.6 km. The road distance is 481 km.
You can take a train from Poissy to Lyon Part Dieu via Paris Gare De Lyon in around 2h 55m.