The average train between Spoleto and Siena takes 5h 54m and the fastest train takes 3h 35m. The train service runs several times per day from Spoleto to Siena. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Spoleto and Siena. The earliest departure is at 5:40 AM in the morning, and the last departure from Spoleto is at 10:05 PM which arrives into Siena at 7:56 AM. All services require a transfer at Orte and take an average of 5h 54m. The schedules shown below are for the next available departures.
Arrives next day


8h 50m • 2 changes
Arrives next day


9h 51m • 2 changes


4h 47m • 2 changes


7h 11m • 2 changes


5h 12m • 2 changes


4h 51m • 2 changes


4h 47m • 2 changes


7h 11m • 2 changes


5h 12m • 2 changes


4h 51m • 2 changes


4h 47m • 2 changes


7h 11m • 2 changes


5h 12m • 2 changes


4h 51m • 2 changes


4h 47m • 2 changes


7h 11m • 2 changes


5h 12m • 2 changes


4h 51m • 2 changes


4h 47m • 2 changes


7h 11m • 2 changes


5h 12m • 2 changes


4h 51m • 2 changes
Want to know about travelling from Spoleto to Siena? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Spoleto to Siena. However, there are services departing from Spoleto station and arriving at Siena station via Orte. The journey, including transfers, takes approximately 5h 54m.
Spoleto to Siena train services, operated by Trenitalia, depart from Spoleto station.
Spoleto to Siena train services, operated by Trenitalia, arrive at Siena station.
Book your Spoleto to Siena train tickets online with Trenitalia and Trenitalia Intercity.
The distance between Spoleto and Siena is 131.3 km. The road distance is 226 km.
You can take a train from Spoleto to Siena via Orte and Chiusi-Chianciano T. in around 4h 50m.