The average train between Nitra and Prague takes 6h 15m and the fastest train takes 6h 13m. The train service runs several times per day from Nitra to Prague. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Nitra and Prague. The earliest departure is at 3:57 AM at night, and the last departure from Nitra is at 6:10 PM which arrives into Prague at 12:25 AM. All services require a transfer, and take on average 6h 15m. The schedules shown below are for the next available departures.

6h 26m • 1 change

6h 13m • 1 change

6h 13m • 1 change

6h 13m • 1 change

6h 26m • 1 change

6h 13m • 1 change

6h 13m • 1 change

6h 13m • 1 change

6h 26m • 1 change

6h 13m • 1 change

6h 13m • 1 change

6h 13m • 1 change

6h 26m • 1 change

6h 13m • 1 change

6h 13m • 1 change

6h 13m • 1 change

6h 26m • 1 change

6h 13m • 1 change

6h 13m • 1 change

6h 13m • 1 change

6h 26m • 1 change

6h 13m • 1 change

6h 13m • 1 change

6h 13m • 1 change
Want to know about travelling from Nitra to Prague? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Nitra to Prague. However, there are services departing from Nitra station and arriving at Prague station via Praha Hlavni Nadrazi. The journey, including transfers, takes approximately 6h 15m.
Nitra to Prague train services, operated by Railways of Slovak Republic (ZSSK), depart from Nove Zamky station.
Nitra to Prague train services, operated by Railways of Slovak Republic (ZSSK), arrive at Praha Hlavni Nadrazi station.
The distance between Nitra and Prague is 331.7 km. The road distance is 521 km.
Railjet operates a train from Nove Zamky to Praha Hlavni Nadrazi 4 times a day. Tickets cost Kč 1,600–2,500 and the journey takes 5h 20m. Two other operators also service this route.