The average train between Nice and Lyon Perrache takes 6h 18m and the fastest train takes 4h 43m. The train service runs several times per day from Nice to Lyon Perrache. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 2 hours between Nice and Lyon Perrache. The earliest departure is at 5:33 AM in the morning, and the last departure from Nice is at 8:25 PM which arrives into Lyon Perrache at 8:34 AM. All services require a transfer at Marseille-Saint-Charles and take an average of 6h 18m. The schedules shown below are for the next available departures.


4h 43m • 2 changes


4h 43m • 2 changes


4h 43m • 2 changes


4h 43m • 2 changes


4h 43m • 2 changes
Want to know about travelling from Nice to Lyon Perrache? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Nice to Lyon Perrache. However, there are services departing from Nice station and arriving at Lyon Perrache station via Marseille-Saint-Charles. The journey, including transfers, takes approximately 6h 18m.
Nice to Lyon Perrache train services, operated by ZOU ! Intermétropole, depart from Nice-Ville station.
Nice to Lyon Perrache train services, operated by ZOU ! Intermétropole, arrive at Lyon Part Dieu station.
Book your Nice to Lyon Perrache train tickets online with ZOU ! Intermétropole, TGV inOui and 2 other operators.
The distance between Nice and Lyon Perrache is 298.1 km. The road distance is 549 km.
You can take a train from Nice-Ville to Lyon Perrache via Marseille-Saint-Charles, Marseille St Charles, and Lyon Part Dieu in around 5h 24m.