The average train between Avignon and Lyon Perrache takes 2h 1m and the fastest train takes 1h 18m. There is a train service every few hours from Avignon to Lyon Perrache. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Avignon and Lyon Perrache. The earliest departure is at 7:15 AM in the morning, and the last departure from Avignon is at 8:50 PM which arrives into Lyon Perrache at 6:29 AM. All services require a transfer, and take on average 2h 1m. The schedules shown below are for the next available departures.

1h 24m • 1 change

1h 22m • 1 change

1h 25m • 1 change

1h 48m • 1 change

1h 22m • 1 change

1h 21m • 1 change

1h 54m • 1 change

1h 18m • 1 change

1h 19m • 1 change

1h 27m • 1 change

2h 6m • 1 change

1h 18m • 1 change

1h 19m • 1 change

1h 27m • 1 change

1h 30m • 1 change

2h 6m • 1 change
Want to know about travelling from Avignon to Lyon Perrache? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Avignon to Lyon Perrache. However, there are services departing from Avignon station and arriving at Lyon Perrache station via Lyon Part Dieu. The journey, including transfers, takes approximately 2h 1m.
Avignon to Lyon Perrache train services, operated by TGV inOui, depart from Avignon Tgv station.
Avignon to Lyon Perrache train services, operated by TGV inOui, arrive at Lyon Part Dieu station.
Book your Avignon to Lyon Perrache train tickets online with TGV inOui, Société Nationale des Chemins de fer Français (SNCF) and Trenitalia.
The distance between Avignon and Lyon Perrache is 200.2 km. The road distance is 232 km.
TGV inOui operates a train from Avignon Tgv to Lyon Part Dieu hourly. Tickets cost €50–80 and the journey takes 1h 4m. Trenitalia also services this route twice daily.