The average train between Naples and Siena takes 5h 28m and the fastest train takes 4h 45m. The train service runs several times per day from Naples to Siena. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 2 hours between Naples and Siena. The earliest departure is at 5:23 AM in the morning, and the last departure from Naples is at 8:30 PM which arrives into Siena at 7:55 AM. All services require a transfer, and take on average 5h 28m. The schedules shown below are for the next available departures.

4h 53m • 1 change

4h 45m • 1 change

4h 57m • 1 change

4h 45m • 1 change

5h 17m • 1 change

5h • 1 change

4h 53m • 1 change

4h 45m • 1 change

4h 53m • 1 change

4h 45m • 1 change

4h 57m • 1 change

4h 45m • 1 change

5h 17m • 1 change

5h • 1 change

4h 53m • 1 change

4h 45m • 1 change

5h 17m • 1 change

5h • 1 change

4h 53m • 1 change

4h 45m • 1 change
Want to know about travelling from Naples to Siena? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Naples to Siena. However, there are services departing from Naples station and arriving at Siena station via Firenze S.M.N.. The journey, including transfers, takes approximately 5h 28m.
Naples to Siena train services, operated by Trenitalia Frecce, depart from Napoli Centrale station.
Naples to Siena train services, operated by Trenitalia Frecce, arrive at Siena station.
Book your Naples to Siena train tickets online with Trenitalia Frecce and Trenitalia.
The distance between Naples and Siena is 365.9 km. The road distance is 567 km.
You can take a train from Napoli Centrale to Siena via Firenze S.M.N. in around 5h 21m.