The average train between Mosbach and Karlsruhe takes 1h 49m and the fastest train takes 1h 30m. There is an hourly train service from Mosbach to Karlsruhe. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Mosbach and Karlsruhe. The earliest departure is at 4:32 AM at night, and the last departure from Mosbach is at 11:07 PM which arrives into Karlsruhe at 1:31 AM. All services require a transfer, and take on average 1h 49m. The schedules shown below are for the next available departures.

2h 1m • 1 change

1h 39m • 1 change

1h 45m • 1 change

2h 1m • 1 change

1h 30m • 1 change

2h 9m • 1 change

1h 56m • 1 change

1h 47m • 1 change

1h 30m • 1 change

2h 9m • 1 change

1h 56m • 1 change

1h 47m • 1 change
Want to know about travelling from Mosbach to Karlsruhe? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mosbach to Karlsruhe. However, there are services departing from Mosbach station and arriving at Karlsruhe station via Heidelberg, Hauptbahnhof. The journey, including transfers, takes approximately 1h 49m.
Mosbach to Karlsruhe train services, operated by Deutsche Bahn Regio (DB Regional), depart from Mosbach, Bahnhof station.
Mosbach to Karlsruhe train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Karlsruhe Hauptbahnhof station.
Book your Mosbach to Karlsruhe train tickets online with Deutsche Bahn Regio (DB Regional), Deutsche Bahn Intercity (DB IC) and Österreichische Bundesbahnen.
The distance between Mosbach and Karlsruhe is 66.4 km. The road distance is 109 km.
You can take a train from Mosbach, Bahnhof to Karlsruhe Hauptbahnhof via Heidelberg, Hauptbahnhof in around 1h 56m.