The average train between Mosbach and Brno takes 16h 41m and the fastest train takes 14h 48m. The train service runs several times per day from Mosbach to Brno. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 3 times a day between Mosbach and Brno. The earliest departure is at 7:53 AM in the morning, and the last departure from Mosbach is at 9:53 PM which arrives into Brno at 2:41 PM. All services require a transfer at Osterburken and take an average of 16h 41m. The schedules shown below are for the next available departures.




14h 48m • 4 changes
Arrives next day




18h 48m • 4 changes
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16h 48m • 4 changes




14h 48m • 4 changes
Arrives next day




18h 48m • 4 changes
Arrives next day




16h 48m • 4 changes




14h 48m • 4 changes
Arrives next day




18h 48m • 4 changes
Arrives next day




16h 48m • 4 changes




14h 48m • 4 changes
Arrives next day




18h 48m • 4 changes
Arrives next day




16h 48m • 4 changes




14h 48m • 4 changes
Arrives next day




18h 48m • 4 changes
Arrives next day




16h 48m • 4 changes
Want to know about travelling from Mosbach to Brno? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mosbach to Brno. However, there are services departing from Mosbach station and arriving at Brno station via Wuerzburg Hbf. The journey, including transfers, takes approximately 16h 41m.
Mosbach to Brno train services, operated by Deutsche Bahn Regio (DB Regional), depart from Osterburken station.
Mosbach to Brno train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Brno Hlavni Nadrazi station.
The distance between Mosbach and Brno is 541 km. The road distance is 862 km.
You can take a train from Mosbach, Bahnhof to Brno Hlavni Nadrazi via Osterburken, Wuerzburg Hbf, Würzburg Hbf, Passau Hbf, Wien Hauptbahnhof, and Wien Hbf in around 11h 15m.