The average train between Molsheim and Lyon takes 5h 2m and the fastest train takes 4h. The train service runs several times per day from Molsheim to Lyon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 3 times a day between Molsheim and Lyon. The earliest departure is at 6:17 AM in the morning, and the last departure from Molsheim is at 10:57 PM which arrives into Lyon at 10:59 AM. All services require a transfer, and take on average 5h 2m. The schedules shown below are for the next available departures.

4h 42m • 1 change
4h 18m • 1 change
4h 31m • 1 change
5h 5m • 1 changeWant to know about travelling from Molsheim to Lyon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Molsheim to Lyon. However, there are services departing from Molsheim station and arriving at Lyon station via Lyon Part Dieu. The journey, including transfers, takes approximately 5h 2m.
Molsheim to Lyon train services, operated by Société Nationale des Chemins de fer Français (SNCF), depart from Strasbourg station.
Molsheim to Lyon train services, operated by Société Nationale des Chemins de fer Français (SNCF), arrive at Lyon Part Dieu station.
Book your Molsheim to Lyon train tickets online with Société Nationale des Chemins de fer Français (SNCF) and TGV inOui.
The distance between Molsheim and Lyon is 369.4 km. The road distance is 523 km.
TGV inOui operates a train from Strasbourg to Lyon Part Dieu every 4 hours. Tickets cost €100–150 and the journey takes 4h 12m. Société Nationale des Chemins de fer Français (SNCF) also services this route twice daily.