The average train between Mayfair and Manchester takes 2h 20m and the fastest train takes 2h 13m. The train runs at least 2 times per hour from Mayfair to Manchester. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 30 minutes between Mayfair and Manchester. The earliest departure is at 6:01 AM in the morning, and the last departure from Mayfair is at 9:55 PM which arrives into Manchester at 12:39 AM. All services require a transfer at Euston station and take an average of 2h 20m. The schedules shown below are for the next available departures.

2h 24m • 1 change

2h 23m • 1 change

2h 28m • 1 change

2h 14m • 1 change
Want to know about travelling from Mayfair to Manchester? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mayfair to Manchester. However, there are services departing from Mayfair station and arriving at Manchester station via Manchester Piccadilly. The journey, including transfers, takes approximately 2h 20m.
Mayfair to Manchester train services, operated by London Underground (Tube), depart from London Euston station.
Mayfair to Manchester train services, operated by London Underground (Tube), arrive at Manchester Piccadilly station.
The distance between Mayfair and Manchester is 260.7 km. The road distance is 296 km.
Avanti West Coast operates a train from London Euston to Manchester Piccadilly every 30 minutes. Tickets cost £65–110 and the journey takes 2h 12m.