The average bus between Mayfair and Manchester takes 4h 45m and the fastest bus takes 4h 15m. There is a bus service every few hours from Mayfair to Manchester. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Mayfair and Manchester. The earliest departure is at 7:15 AM in the morning, and the last departure from Mayfair is at 8:58 PM which arrives into Manchester at 2:00 AM. All services require a transfer at Finchley Road / O2 Centre and take an average of 4h 45m. The schedules shown below are for the next available departures.

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Want to know about travelling from Mayfair to Manchester? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Mayfair to Manchester. However, there are services departing from Mayfair station and arriving at Manchester station via Manchester, Shudehill Interchange. The journey, including transfers, takes approximately 4h 45m.
Mayfair to Manchester bus services, operated by Metroline Travel, depart from London, Finchley Road ("Subway" restaurant) station.
Mayfair to Manchester bus services, operated by Metroline Travel, arrive at Manchester, Shudehill Interchange station.
The distance between Mayfair and Manchester is 260.7 km. The road distance is 314 km.
FlixBus operates a bus from London, Finchley Road ("Subway" restaurant) to Manchester, Shudehill Interchange hourly. Tickets cost £18–35 and the journey takes 4h 10m.