The average train between Mayen and Rome takes 20h 40m and the fastest train takes 14h 35m. The train service runs several times per day from Mayen to Rome. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 3 times a day between Mayen and Rome. The earliest departure is at 8:49 AM in the morning, and the last departure from Mayen is at 8:56 PM which arrives into Rome at 7:19 PM. All services require a transfer at Andernach and take an average of 20h 40m. The schedules shown below are for the next available departures.





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24h 23m • 5 changesWant to know about travelling from Mayen to Rome? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mayen to Rome. However, there are services departing from Mayen station and arriving at Rome station via Koeln Hbf. The journey, including transfers, takes approximately 20h 40m.
Mayen to Rome train services, operated by Deutsche Bahn Regio (DB Regional), depart from Andernach station.
Mayen to Rome train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Roma Termini station.
Book your Mayen to Rome train tickets online with Deutsche Bahn Regio (DB Regional), National Express and 3 other operators.
The distance between Mayen and Rome is 1,020.9 km. The road distance is 1,500 km.
You can take a train from Mayen Westbahnhof to Roma Termini via Andernach, Köln Hbf, Basel SBB, Lugano, and Milano Centrale in around 15h 29m.