The average train between Mattoon and Milwaukee takes 8h 9m and the fastest train takes 5h 1m. The train service runs several times per day from Mattoon to Milwaukee. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 3 times a day between Mattoon and Milwaukee. The earliest departure is at 5:23 AM in the morning, and the last departure from Mattoon is at 6:19 PM which arrives into Milwaukee at 7:39 AM. All services require a transfer, and take on average 8h 9m. The schedules shown below are for the next available departures.

7h 11m • 1 change

5h 1m • 1 change
Arrives next day

13h 20m • 1 change

7h 11m • 1 change

5h 1m • 1 change
Arrives next day

6h 35m • 1 change

7h 11m • 1 change

5h 1m • 1 change
Arrives next day

15h 35m • 1 change

7h 11m • 1 change

5h 1m • 1 change
Arrives next day

15h 35m • 1 change
Want to know about travelling from Mattoon to Milwaukee? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mattoon to Milwaukee. However, there are services departing from Mattoon station and arriving at Milwaukee station via Chicago Union Station station. The journey, including transfers, takes approximately 8h 9m.
Mattoon to Milwaukee train services, operated by Amtrak, depart from Mattoon Amtrak Station.
Mattoon to Milwaukee train services, operated by Amtrak, arrive at Milwaukee station.
Book your Mattoon to Milwaukee train tickets online with Amtrak.
The distance between Mattoon and Milwaukee is 397.3 km. The road distance is 414 km.
You can take a train from Mattoon Amtrak Station to Milwaukee via Chicago Union Station in around 5h 56m.