There are 7 ways to get from Mattoon to Milwaukee by train (Amtrak), train, bus, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train (Amtrak)
best- Take the train from Mattoon Amtrak Station to Chicago Union Stationtrain Saluki / ...
- Take the train from Chicago Union Station to Milwaukeetrain Hiawatha Service / ...
5h 56m$140–221Drive 270.9 mi
cheapest- Drive from Mattoon to Milwaukeecar 270.9 mi
4h 40m$47–67Train, bus via Champaign
- Take the train from Mattoon Amtrak Station to Champaign-Urbanatrain
- Take the bus from Champaign Intermodal Trans Ctr to Chicago Bus Stationbus
- Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus
6h 50m$83–123Train to University Of Illinois Willard Airport, fly to Chicago O'Hare International Airport, bus
- Take the train from Mattoon Amtrak Station to Champaign-Urbanatrain
- Fly from University Of Illinois Willard Airport (CMI) to Chicago O'Hare International Airport (ORD)plane CMI - ORD
- Take the bus from Chicago to Milwaukee Intermodal Stationbus
5h 50m$88–317Train, bus
- Take the train from Mattoon Amtrak Station to Chicago Union Stationtrain Saluki / ...
- Take the bus from Chicago Bus Station to Milwaukee Mitchell Airportbus FlixBus 2548 / ...
6h 52m$111–169Train to Chicago O'Hare International Airport, fly to General Mitchell International Airport
- Take the train from Mattoon Amtrak Station to Homewoodtrain
- Fly from Chicago O'Hare International Airport (ORD) to General Mitchell International Airport (MKE)plane ORD - MKE
7h 22m$791–1,090Train to Chicago Midway International Airport, fly to General Mitchell International Airport
- Take the train from Mattoon Amtrak Station to Homewoodtrain
- Fly from Chicago Midway International Airport (MDW) to General Mitchell International Airport (MKE)plane MDW - MKE
7h 2m$156–690
Mattoon to Milwaukee by train (Amtrak)
Comparing Your Travel Options
The cheapest way to get from Mattoon to Milwaukee is to drive which costs $45 - $70 and takes 4h 40m.
The fastest way to get from Mattoon to Milwaukee is to drive which takes 4h 40m and costs $45 - $70.
No, there is no direct train from Mattoon station to Milwaukee. However, there are services departing from Mattoon Amtrak Station and arriving at Milwaukee via Chicago Union Station. The journey, including transfers, takes approximately 5h 56m.
The distance between Mattoon and Milwaukee is 259 miles. The road distance is 272.5 miles.
The best way to get from Mattoon to Milwaukee without a car is to train which takes 5h 56m and costs $140 - $230.
It takes approximately 5h 56m to get from Mattoon to Milwaukee, including transfers.
Mattoon to Milwaukee train services, operated by Amtrak, depart from Mattoon Amtrak Station.
Mattoon to Milwaukee train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Mattoon to Milwaukee is 273 miles. It takes approximately 4h 40m to drive from Mattoon to Milwaukee.
Book your Mattoon to Milwaukee train tickets online with Omio.
What companies run services between Mattoon, IL, USA and Milwaukee, WI, USA?
You can take a train from Mattoon Amtrak Station to Milwaukee via Chicago Union Station in around 5h 56m.
- Website
- united.com
Flights from Chicago O'Hare International Airport to General Mitchell International Airport
- Ave. Duration
- 1h 3m
- When
- Every day
- Estimated price
- $40–320
- Website
- aa.com
Flights from University Of Illinois Willard Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 22m
- When
- Every day
- Estimated price
- $30–230
Flights from Chicago O'Hare International Airport to General Mitchell International Airport
- Ave. Duration
- 1h 2m
- When
- Every day
- Estimated price
- $40–320
- Website
- southwest.com
Flights from Chicago Midway International Airport to General Mitchell International Airport
- Ave. Duration
- 51 min
- When
- Every day
- Estimated price
- $65–550
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Mattoon Amtrak Station to Chicago Union Station
- Ave. Duration
- 3h 27m
- Frequency
- 3 times a day
- Estimated price
- $95–150
- Website
- Amtrak
Train from Chicago Union Station to Milwaukee
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $45–75
- Website
- Amtrak
Train from Mattoon Amtrak Station to Champaign-Urbana
- Ave. Duration
- 51 min
- Frequency
- 3 times a day
- Estimated price
- $24–40
- Website
- Amtrak
Train from Mattoon Amtrak Station to Champaign-Urbana
- Ave. Duration
- 51 min
- Frequency
- 3 times a day
- Estimated price
- $24–40
- Website
- Amtrak
Train from Mattoon Amtrak Station to Chicago Union Station
- Ave. Duration
- 3h 27m
- Frequency
- 3 times a day
- Estimated price
- $95–150
- Website
- Amtrak
Train from Mattoon Amtrak Station to Homewood
- Ave. Duration
- 2h 37m
- Frequency
- 3 times a day
- Estimated price
- $80–130
- Website
- Amtrak
Train from Mattoon Amtrak Station to Homewood
- Ave. Duration
- 2h 37m
- Frequency
- 3 times a day
- Estimated price
- $80–130
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Champaign Intermodal Trans Ctr to Chicago Bus Station
- Ave. Duration
- 2h 25m
- Frequency
- 4 times a day
- Estimated price
- $21–35
- Schedules at
- Flixbus USA
Bus from Chicago Bus Station to Milwaukee Intermodal Station
- Ave. Duration
- 1h 55m
- Frequency
- 5 times a day
- Estimated price
- $14–21
- Schedules at
- Flixbus USA
Bus from Chicago Bus Station to Milwaukee Mitchell Airport
- Ave. Duration
- 1h 35m
- Frequency
- 5 times a day
- Estimated price
- $13–20
- Schedules at
- Flixbus USA
- Phone
- +1 800-448-0572
- ticketsales@peoriacharter.com
- Website
- Peoria Charter
Bus from Champaign Intermodal Trans Ctr to Chicago Bus Station
- Ave. Duration
- 3h 10m
- Frequency
- Twice daily
- Estimated price
- $45–60
- Website
- Peoria Charter
- Schedules at
- Peoria Charter Schedules
- cash
- $60
- online
- $45
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Chicago Bus Station to Milwaukee Intermodal Station
- Ave. Duration
- 1h 40m
- Frequency
- Every 4 hours
- Estimated price
- $16–25
- Website
- Greyhound
Bus from Chicago to Milwaukee Intermodal Station
- Ave. Duration
- 1h 20m
- Frequency
- Twice daily
- Estimated price
- $14–22
- Website
- Greyhound
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide
Booking & Getting There
There are 322+ hotels available in Milwaukee.







