The average train between Mannheim and Iserlohn takes 3h 31m and the fastest train takes 3h 4m. There is a train service every few hours from Mannheim to Iserlohn. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Mannheim and Iserlohn. The earliest departure is at 6:34 AM in the morning, and the last departure from Mannheim is at 8:39 PM which arrives into Iserlohn at 1:06 AM. All services require a transfer, and take on average 3h 31m. The schedules shown below are for the next available departures.

3h 4m • 1 change

3h 4m • 1 change

3h 59m • 1 change

3h 5m • 1 change

3h 4m • 1 change

3h 4m • 1 change

3h 59m • 1 change

3h 4m • 1 change

3h 4m • 1 change

3h 4m • 1 change

3h 59m • 1 change

3h 4m • 1 change

3h 4m • 1 change

3h 4m • 1 change

3h 59m • 1 change

3h 4m • 1 change

3h 4m • 1 change

3h 4m • 1 change

3h 59m • 1 change

3h 4m • 1 change
Want to know about travelling from Mannheim to Iserlohn? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mannheim to Iserlohn. However, there are services departing from Mannheim station and arriving at Iserlohn station via Hagen Hbf. The journey, including transfers, takes approximately 3h 31m.
Mannheim to Iserlohn train services, operated by Deutsche Bahn Intercity (DB IC), depart from Mannheim, Hauptbahnhof station.
Mannheim to Iserlohn train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Hagen Hbf station.
Book your Mannheim to Iserlohn train tickets online with Deutsche Bahn Intercity (DB IC) and VIAS Rail GmbH.
The distance between Mannheim and Iserlohn is 216.6 km. The road distance is 338 km.
Deutsche Bahn Intercity (DB IC) operates a train from Mannheim, Hauptbahnhof to Hagen Hbf hourly. Tickets cost €55–200 and the journey takes 2h 24m.