The average train between Prague and Iserlohn takes 10h 34m and the fastest train takes 8h 57m. The train service runs several times per day from Prague to Iserlohn. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 4 times a day between Prague and Iserlohn. The earliest departure is at 6:41 AM in the morning, and the last departure from Prague is at 4:41 PM which arrives into Iserlohn at 10:38 AM. All services require a transfer at S Spandau Bhf and take an average of 10h 34m. The schedules shown below are for the next available departures.


8h 57m • 2 changes


8h 57m • 2 changes


8h 58m • 2 changes


8h 58m • 2 changes


8h 57m • 2 changes


8h 57m • 2 changes


8h 58m • 2 changes


8h 58m • 2 changes


8h 57m • 2 changes


8h 57m • 2 changes


8h 58m • 2 changes
Arrives next day


10h 25m • 2 changes
Want to know about travelling from Prague to Iserlohn? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Prague to Iserlohn. However, there are services departing from Prague station and arriving at Iserlohn station via Berlin-Spandau. The journey, including transfers, takes approximately 10h 34m.
Prague to Iserlohn train services, operated by Railjet, depart from Praha-Holesovice station.
Prague to Iserlohn train services, operated by Railjet, arrive at Hagen Hbf station.
Book your Prague to Iserlohn train tickets online with Railjet, Deutsche Bahn Intercity (DB IC) and 2 other operators.
The distance between Prague and Iserlohn is 493.8 km. The road distance is 870 km.
You can take a train from Praha-Holesovice to Iserlohn via S Spandau Bhf and Hagen Hbf in around 8h 49m.