The average train between Manfredonia and Rome takes 5h 1m and the fastest train takes 4h 23m. The train service runs several times per day from Manfredonia to Rome. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 4 times a day between Manfredonia and Rome. The earliest departure is at 7:38 AM in the morning, and the last departure from Manfredonia is at 6:42 PM which arrives into Rome at 12:02 AM. All services require a transfer, and take on average 5h 1m. The schedules shown below are for the next available departures.

4h 27m • 1 change

5h 15m • 1 change

5h 10m • 1 change

5h 16m • 1 change

4h 27m • 1 change

5h 15m • 1 change

5h 10m • 1 change

4h 23m • 1 change

5h 17m • 1 change

5h 15m • 1 change

5h 10m • 1 change

4h 23m • 1 change

5h 17m • 1 change

5h 15m • 1 change

5h 10m • 1 change

4h 23m • 1 change

4h 27m • 1 change

5h 39m • 1 change

5h 15m • 1 change

5h 10m • 1 change

4h 27m • 1 change

5h 15m • 1 change

5h 10m • 1 change

5h 46m • 1 change
Want to know about travelling from Manfredonia to Rome? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Manfredonia to Rome. However, there are services departing from Manfredonia station and arriving at Rome station via Roma Termini. The journey, including transfers, takes approximately 5h 1m.
Manfredonia to Rome train services, operated by Trenitalia, depart from Foggia station.
Manfredonia to Rome train services, operated by Trenitalia, arrive at Roma Termini station.
Book your Manfredonia to Rome train tickets online with Trenitalia, Trenitalia Frecce and Trenitalia Intercity.
The distance between Manfredonia and Rome is 285 km. The road distance is 391 km.
Trenitalia Frecce operates a train from Foggia to Roma Termini every 4 hours. Tickets cost €50–100 and the journey takes 3h 20m. Two other operators also service this route.