The average train between Manchester and Slough takes 3h 10m and the fastest train takes 2h 56m. The train service runs several times per day from Manchester to Slough. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Manchester and Slough. The earliest departure is at 5:05 AM in the morning, and the last departure from Manchester is at 8:15 PM which arrives into Slough at 12:28 AM. All services require a transfer at London Euston and take an average of 3h 10m. The schedules shown below are for the next available departures.
Want to know about travelling from Manchester to Slough? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Manchester to Slough. However, there are services departing from Manchester station and arriving at Slough station via London Euston. The journey, including transfers, takes approximately 3h 10m.
Manchester to Slough train services, operated by Avanti West Coast, depart from Manchester Piccadilly station.
Manchester to Slough train services, operated by Avanti West Coast, arrive at Slough station.
Book your Manchester to Slough train tickets online with Avanti West Coast, London Underground (Tube) and Elizabeth Line (TfL).
The distance between Manchester and Slough is 245.8 km. The road distance is 328 km.
You can take a train from Manchester Piccadilly to Slough via London Euston, Euston station, Tottenham Court Road station, and Tottenham Court Rd in around 2h 58m.