Bus Manchester to Slough from £23 | Tickets & Timetables

Trip Overview

The average bus between Manchester and Slough takes 5h 49m and the fastest bus takes 5h 16m. The bus service runs several times per day from Manchester to Slough. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

5h 49m
Duration: 206 mi
Distance: £23
Average price: Every 4 hours
Frequency

Bus

best

Take the bus from Manchester, Shudehill Interchange to London Heathrow Airportbus Uk980 / ...

5h 31m

£19–35

Manchester to Slough bus times

Buses run every 4 hours between Manchester and Slough. The earliest departure is at 4:50 AM at night, and the last departure from Manchester is at 11:59 PM which arrives into Slough at 5:57 AM. All services require a transfer at London Heathrow Airport and take an average of 5h 49m. The schedules shown below are for the next available departures.

Departing Monday, April 27, 2026

11:10 PM → 4:27 AM
Arrives next day
5h 17m • 1 change
11:59 PM → 5:58 AM
Arrives next day
5h 59m • 1 change

Departing Tuesday, April 28, 2026

4:50 AM → 10:22 AM
5h 32m • 1 change
8:30 AM → 2:13 PM
5h 43m • 1 change
1:40 PM → 7:48 PM
6h 8m • 1 change
3:10 PM → 9:29 PM
6h 19m • 1 change
Show more

Departing Wednesday, April 29, 2026

4:50 AM → 10:22 AM
5h 32m • 1 change
8:30 AM → 2:13 PM
5h 43m • 1 change
1:40 PM → 7:48 PM
6h 8m • 1 change
3:10 PM → 9:29 PM
6h 19m • 1 change
Show more

Departing Thursday, April 30, 2026

4:50 AM → 10:22 AM
5h 32m • 1 change
8:30 AM → 2:13 PM
5h 43m • 1 change
1:40 PM → 7:48 PM
6h 8m • 1 change
3:10 PM → 9:29 PM
6h 19m • 1 change
Show more

Departing Friday, May 1, 2026

4:50 AM → 10:22 AM
5h 32m • 1 change
8:30 AM → 2:13 PM
5h 43m • 1 change
1:40 PM → 7:48 PM
6h 8m • 1 change
3:10 PM → 9:29 PM
6h 19m • 1 change
Show more

Departing Saturday, May 2, 2026

4:50 AM → 10:24 AM
5h 34m • 1 change
8:30 AM → 2:29 PM
5h 59m • 1 change
1:40 PM → 7:44 PM
6h 4m • 1 change
3:10 PM → 9:03 PM
5h 53m • 1 change
Show more

Departing Sunday, May 3, 2026

4:50 AM → 10:23 AM
5h 33m • 1 change
8:30 AM → 2:26 PM
5h 56m • 1 change
1:40 PM → 7:53 PM
6h 13m • 1 change
3:10 PM → 9:02 PM
5h 52m • 1 change

Frequently asked questions

Want to know about travelling from Manchester to Slough? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.