Train Manchester to Prestwick from £114 | Tickets & Timetables

Trip Overview

The average train between Manchester and Prestwick takes 4h 39m and the fastest train takes 4h 5m. There is an hourly train service from Manchester to Prestwick. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 39m
Duration: 259 mi
Distance: £114
Average price: Hourly
Frequency

Train

best

Take the train from Manchester Oxford Road to Prestontrain
Take the train from Preston to Glasgow Centraltrain
Take the train from Glasgow Central to Prestwick Towntrain

4h 37m

£72–172

Manchester to Prestwick train times

Trains run hourly between Manchester and Prestwick. The earliest departure is at 5:52 AM in the morning, and the last departure from Manchester is at 11:36 PM which arrives into Prestwick at 8:15 AM. All services require a transfer at Preston and take an average of 4h 39m. The schedules shown below are for the next available departures.

Departing Sunday, May 17, 2026

5:30 PM → 9:44 PM
4h 14m • 2 changes
6:52 PM → 11:46 PM
4h 54m • 2 changes
8:30 PM → 6:46 AM
Arrives next day
10h 16m • 2 changes
11:04 PM → 9:16 AM
Arrives next day
10h 11m • 2 changes

Departing Monday, May 18, 2026

5:52 AM → 10:14 AM
4h 22m • 2 changes
7:25 AM → 11:49 AM
4h 24m • 2 changes
7:53 AM → 12:15 PM
4h 21m • 2 changes
8:53 AM → 1:17 PM
4h 23m • 2 changes
Show more

Departing Tuesday, May 19, 2026

5:52 AM → 10:14 AM
4h 22m • 2 changes
7:25 AM → 11:49 AM
4h 24m • 2 changes
7:53 AM → 12:15 PM
4h 21m • 2 changes
8:53 AM → 1:17 PM
4h 23m • 2 changes
Show more

Frequently asked questions

Want to know about travelling from Manchester to Prestwick? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.