The average train between Manchester and Enschede takes 9h 40m and the fastest train takes 8h 19m. The train service runs several times per day from Manchester to Enschede. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 4 times a day between Manchester and Enschede. The earliest departure is at 5:05 AM in the morning, and the last departure from Manchester is at 10:15 PM which arrives into Enschede at 1:14 PM. All services require a transfer at London Euston and take an average of 9h 40m. The schedules shown below are for the next available departures.



9h 19m • 3 changes



9h 39m • 3 changes



9h 39m • 3 changes
Arrives next day



9h 39m • 3 changes



9h 19m • 3 changes



9h 39m • 3 changes



9h 39m • 3 changes
Arrives next day



9h 39m • 3 changes



10h 9m • 3 changes



9h 39m • 3 changes



9h 39m • 3 changes
Arrives next day



18h 59m • 3 changes



9h 19m • 3 changes



9h 39m • 3 changes



9h 39m • 3 changes
Arrives next day



9h 39m • 3 changes
Want to know about travelling from Manchester to Enschede? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Manchester to Enschede. However, there are services departing from Manchester station and arriving at Enschede station via London Euston. The journey, including transfers, takes approximately 9h 40m.
Manchester to Enschede train services, operated by Avanti West Coast, depart from Manchester Piccadilly station.
Manchester to Enschede train services, operated by Avanti West Coast, arrive at Enschede station.
Book your Manchester to Enschede train tickets online with Avanti West Coast and Nederlandse Spoorwegen (NS).
The distance between Manchester and Enschede is 628.7 km. The road distance is 998 km.
You can take a train from Manchester Piccadilly to Enschede via London Euston, London St. Pancras Int., Rotterdam Centraal, and Utrecht Centraal in around 9h 27m.