The average train between Manchester and Enschede takes 12h 17m and the fastest train takes 8h 44m. The train service runs several times per day from Manchester to Enschede. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 5 times a day between Manchester and Enschede. The earliest departure is at 6:30 AM in the morning, and the last departure from Manchester is at 10:15 PM which arrives into Enschede at 3:44 PM. All services require a transfer at London Euston and take an average of 12h 17m. The schedules shown below are for the next available departures.




9h 44m • 4 changes



11h 9m • 4 changes



10h 39m • 4 changes



9h 39m • 4 changes



9h 44m • 4 changes



11h 9m • 4 changes



10h 39m • 4 changes



9h 39m • 4 changes



9h 14m • 4 changes



10h 39m • 4 changes



9h 39m • 4 changes



9h 39m • 4 changes



8h 44m • 4 changes



10h 9m • 4 changes



10h 9m • 4 changes



9h 9m • 4 changesWant to know about travelling from Manchester to Enschede? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Manchester to Enschede. However, there are services departing from Manchester Piccadilly station and arriving at Enschede station via London Euston station, Brussel-Zuid / Bruxelles-Midi station and Rotterdam Centraal station. The journey, including transfers, takes approximately 12h 17m.
Manchester to Enschede train services, operated by Avanti West Coast, depart from Manchester Piccadilly station.
Manchester to Enschede train services, operated by Nederlandse Spoorwegen (NS), arrive at Enschede station.
Book your Manchester to Enschede train tickets online with Omio.
The distance between Manchester and Enschede is 628.7 km.
You can take a train from Manchester Piccadilly to Enschede via London Euston, London St Pancras Intl, Brussel-Zuid / Bruxelles-Midi, Rotterdam Centraal, and Gouda in around 9h 35m.