The average train between Manchester and Cambridge takes 3h 53m and the fastest train takes 3h 26m. There is a train service every few hours from Manchester to Cambridge. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Manchester and Cambridge. The earliest departure is at 5:05 AM in the morning, and the last departure from Manchester is at 10:15 PM which arrives into Cambridge at 8:10 AM. All services require a transfer, and take on average 3h 53m. The schedules shown below are for the next available departures.

4h 4m • 1 change

3h 39m • 1 change

3h 28m • 1 change

3h 27m • 1 change

4h 4m • 1 change

3h 39m • 1 change

3h 28m • 1 change

3h 27m • 1 change

4h 4m • 1 change

3h 39m • 1 change

3h 28m • 1 change

3h 27m • 1 change
Want to know about travelling from Manchester to Cambridge? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Manchester to Cambridge. However, there are services departing from Manchester station and arriving at Cambridge station via Nuneaton. The journey, including transfers, takes approximately 3h 53m.
Manchester to Cambridge train services, operated by Avanti West Coast, depart from Manchester Piccadilly station.
Manchester to Cambridge train services, operated by Avanti West Coast, arrive at Cambridge station.
Book your Manchester to Cambridge train tickets online with Avanti West Coast and Cross Country.
The distance between Manchester and Cambridge is 212.8 km. The road distance is 324 km.
You can take a train from Manchester Piccadilly to Cambridge via Nuneaton in around 4h 3m.