The average train between Mainz and Zwickau takes 7h 18m and the fastest train takes 5h 34m. The train service runs several times per day from Mainz to Zwickau. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 3 times a day between Mainz and Zwickau. The earliest departure is at 8:34 AM in the morning, and the last departure from Mainz is at 11:14 PM which arrives into Zwickau at 2:08 PM. All services require a transfer at Frankfurt and take an average of 7h 18m. The schedules shown below are for the next available departures.



7h 41m • 3 changes



7h 54m • 3 changes
Arrives next day



14h 54m • 3 changes



5h 34m • 3 changes



6h 21m • 3 changes



6h 34m • 3 changes



5h 34m • 3 changes



6h 21m • 3 changes



6h 34m • 3 changes
Want to know about travelling from Mainz to Zwickau? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mainz to Zwickau. However, there are services departing from Mainz station and arriving at Zwickau station via Erfurt Hbf. The journey, including transfers, takes approximately 7h 18m.
Mainz to Zwickau train services, operated by vlexx, depart from Frankfurt station.
Mainz to Zwickau train services, operated by vlexx, arrive at Zwickau, Hauptbahnhof station.
Book your Mainz to Zwickau train tickets online with vlexx, Deutsche Bahn Intercity (DB IC) and Deutsche Bahn Regio (DB Regional).
The distance between Mainz and Zwickau is 309.8 km. The road distance is 494 km.
You can take a train from Mainz, Römisches Theater to Zwickau, Hauptbahnhof via Frankfurt, Erfurt Hbf, and Leipzig Hbf in around 6h 7m.