The average train between Mainz and Spa takes 5h 18m and the fastest train takes 4h 9m. The train service runs several times per day from Mainz to Spa. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Mainz and Spa. The earliest departure is at 6:14 AM in the morning, and the last departure from Mainz is at 7:35 PM which arrives into Spa at 7:23 AM. All services require a transfer at Frankfurt and take an average of 5h 18m. The schedules shown below are for the next available departures.



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4h 9m • 3 changesWant to know about travelling from Mainz to Spa? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mainz to Spa. However, there are services departing from Mainz station and arriving at Spa station via Frankfurt. The journey, including transfers, takes approximately 5h 18m.
Mainz to Spa train services, operated by Deutsche Bahn Regio (DB Regional), depart from Mainz, Römisches Theater station.
Mainz to Spa train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Spa-Géronstère station.
Book your Mainz to Spa train tickets online with Deutsche Bahn Regio (DB Regional), Deutsche Bahn Intercity (DB IC) and 3 other operators.
The distance between Mainz and Spa is 180.9 km. The road distance is 309 km.
You can take a train from Mainz, Römisches Theater to Spa-Géronstère via Frankfurt, Aachen Hbf, and Pepinster in around 5h 17m.