The average train between Mainz and Arnhem takes 3h 44m and the fastest train takes 3h 12m. The train service runs several times per day from Mainz to Arnhem. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 3 hours between Mainz and Arnhem. The earliest departure is at 2:04 AM at night, and the last departure from Mainz is at 7:14 PM which arrives into Arnhem at 10:26 PM. All services require a transfer, and take on average 3h 44m. The schedules shown below are for the next available departures.

3h 12m • 1 change

3h 12m • 1 change

3h 12m • 1 change

3h 12m • 1 change

5h 39m • 1 change

3h 17m • 1 change

3h 13m • 1 change

3h 12m • 1 change

5h 39m • 1 change

3h 17m • 1 change

3h 13m • 1 change

3h 12m • 1 change

5h 39m • 1 change

3h 17m • 1 change

3h 13m • 1 change

3h 12m • 1 change

5h 39m • 1 change

3h 17m • 1 change

3h 13m • 1 change

3h 12m • 1 change

6h 52m • 1 change

4h 12m • 1 change

4h 12m • 1 change

4h 12m • 1 change
Want to know about travelling from Mainz to Arnhem? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mainz to Arnhem. However, there are services departing from Mainz station and arriving at Arnhem station via Arnhem Centraal. The journey, including transfers, takes approximately 3h 44m.
Mainz to Arnhem train services, operated by vlexx, depart from Frankfurt station.
Mainz to Arnhem train services, operated by vlexx, arrive at Arnhem Centraal station.
Book your Mainz to Arnhem train tickets online with vlexx, Deutsche Bahn Intercity (DB IC) and 3 other operators.
The distance between Mainz and Arnhem is 277 km. The road distance is 357 km.
Deutsche Bahn Intercity (DB IC) operates a train from Frankfurt to Arnhem Centraal every 3 hours. Tickets cost €60–270 and the journey takes 2h 40m. Nederlandse Spoorwegen (NS) also services this route every 3 hours.