The average train between Lucerne and Mainz takes 5h 1m and the fastest train takes 4h 21m. There is a train service every few hours from Lucerne to Mainz. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Lucerne and Mainz. The earliest departure is at 12:47 AM at night, and the last departure from Lucerne is at 11:54 PM which arrives into Mainz at 8:33 AM. All services require a transfer at Basel SBB and take an average of 5h 1m. The schedules shown below are for the next available departures.


7h 56m • 2 changes


4h 24m • 2 changes


4h 52m • 2 changes


4h 24m • 2 changes


7h 56m • 2 changes


4h 24m • 2 changes


4h 49m • 2 changes


4h 24m • 2 changes


4h 24m • 2 changes


5h 16m • 2 changes


4h 24m • 2 changes


4h 49m • 2 changes


4h 24m • 2 changes


5h 16m • 2 changes


4h 24m • 2 changes


4h 49m • 2 changes
Want to know about travelling from Lucerne to Mainz? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Lucerne to Mainz. However, there are services departing from Lucerne station and arriving at Mainz station via Basel SBB. The journey, including transfers, takes approximately 5h 1m.
Lucerne to Mainz train services, operated by Swiss Federal Railways (SBB CFF FFS), depart from Luzern station.
Lucerne to Mainz train services, operated by Swiss Federal Railways (SBB CFF FFS), arrive at Mainz, Hauptbahnhof station.
Book your Lucerne to Mainz train tickets online with Swiss Federal Railways (SBB CFF FFS), Deutsche Bahn Intercity (DB IC) and 3 other operators.
The distance between Lucerne and Mainz is 326.2 km. The road distance is 416 km.
You can take a train from Luzern to Mainz, Hauptbahnhof via Basel SBB and Mannheim, Hauptbahnhof in around 4h 27m.