The average train between Lille and Prague takes 16h 54m and the fastest train takes 12h 52m. The train service runs several times per day from Lille to Prague. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 4 times a day between Lille and Prague. The earliest departure is at 7:18 AM in the morning, and the last departure from Lille is at 10:09 PM which arrives into Prague at 6:21 PM. All services require a transfer at Brussels-Midi and take an average of 16h 54m. The schedules shown below are for the next available departures.




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12h 52m • 4 changesArrives next day




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12h 52m • 4 changesArrives next day




18h 51m • 4 changesArrives next day




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12h 52m • 4 changesArrives next day




18h 51m • 4 changesArrives next day




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12h 52m • 4 changesArrives next day




18h 51m • 4 changesArrives next day




18h 51m • 4 changesWant to know about travelling from Lille to Prague? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Lille to Prague. However, there are services departing from Lille Europe station and arriving at Praha Hlavni Nadrazi station via Brussel-Zuid / Bruxelles-Midi station, Frankfurt station, Nürnberg Hbf station and Schwandorf station. The journey, including transfers, takes approximately 16h 54m.
Lille to Prague train services, operated by TGV inOui, depart from Lille Europe station.
Lille to Prague train services, operated by Die Länderbahn, arrive at Praha Hlavni Nadrazi station.
Book your Lille to Prague train tickets online with Omio.
The distance between Lille and Prague is 807.5 km. The road distance is 955 km.
You can take a train from Lille Europe to Praha Hlavni Nadrazi via Brussels-Midi, Bruxelles Midi, Frankfurt, Nürnberg Hbf, and Schwandorf in around 13h 15m.